Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23986236 | 1.00 | PKM (0.57) | PKMTP53TSHRPLA2G4BALDH1A1 | |
| SCHEMBL23986233 | 0.95 | TP53 (0.58) | PKMTP53TSHRPLA2G4BALDH1A1 | |
| SCHEMBL28722712 | 0.95 | TP53 (0.58) | PKMTP53TSHRPLA2G4BALDH1A1 | |
| SCHEMBL28718548 | 0.94 | TP53 (0.60) | PKMTP53TSHRPLA2G4BALDH1A1 | |
| SCHEMBL23986568 | 0.94 | TP53 (0.60) | PKMTP53TSHRPLA2G4BALDH1A1 | |
| SCHEMBL28708025 | 0.94 | TP53 (0.60) | PKMTP53TSHRPLA2G4BALDH1A1 | |
| SCHEMBL23986318 | 0.94 | TP53 (0.60) | PKMTP53TSHRPLA2G4BALDH1A1 | |
| SCHEMBL23986312 | 0.94 | PKM (0.57) | PKMTP53TSHRPLA2G4BALDH1A1 | |
| SCHEMBL28301263 | 0.94 | PKM (0.57) | PKMTP53TSHRPLA2G4BALDH1A1 | |
| SCHEMBL177170 | 0.90 | PKM (0.69) | PKMTP53TSHRPLA2G4BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114262321-B | Bistable light-regulated small molecular protein degradation agent, preparation method and application | 中国药科大学 | 2024-08-09 | — | — | CN | disclosed |
| CN-114262321-A | Bistable light-regulated small-molecule protein degradation agent, preparation method and application | 中国药科大学 | 2022-04-01 | — | — | CN | disclosed |