Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.70 |
| ▸ | CA9 | Q16790 | 4/20 | 0.67 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.62 |
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.62 |
| ▸ | NT5E | P21589 | 2/20 | 0.62 |
| ▸ | TOP2A | P11388 | 1/20 | 0.62 |
| ▸ | RELA | Q04206 | 1/20 | 0.62 |
| ▸ | PTGES | O14684 | 1/20 | 0.59 |
| ▸ | PRKCG | P05129 | 1/20 | 0.57 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.56 |
| ▸ | ALB | P02768 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GLI1 | P08151 | 1/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | DPP4 | P27487 | 1/20 | 0.56 |
| ▸ | RORC | P51449 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16272376 | 1.00 | SLC10A1 (0.70) | SLC10A1CA9CA1CA2PTPN1 | |
| SCHEMBL16263918 | 1.00 | SLC10A1 (0.70) | SLC10A1CA9CA1CA2PTPN1 | |
| SCHEMBL16979310 | 1.00 | SLC10A1 (0.70) | SLC10A1CA9CA1CA2PTPN1 | |
| SCHEMBL14374364 | 0.91 | CA9 (0.61) | SLC10A1CA9CA1CA2PTPN1 | |
| SCHEMBL25748597 | 0.91 | SLC10A1 (0.71) | SLC10A1CA9CA1CA2PTPN1 | |
| SCHEMBL13098063 | 0.91 | PTPN1 (0.76) | SLC10A1CA9CA1CA2PTPN1 | |
| SCHEMBL16994315 | 0.91 | PTPN1 (0.76) | SLC10A1CA9CA1CA2PTPN1 | |
| SCHEMBL2733084 | 0.91 | PTPN1 (0.76) | SLC10A1CA9CA1CA2PTPN1 | |
| SCHEMBL6112842 | 0.91 | PTPN1 (0.76) | SLC10A1CA9CA1CA2PTPN1 | |
| SCHEMBL214201 | 0.91 | PTPN1 (0.76) | SLC10A1CA9CA1CA2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170348324-A1 | DERIVATIVES OF BETULIN | GLAXOSMITHKLINE LLC (US) | 2017-12-07 | — | — | US | disclosed |
| US-20170252356-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING HIV WITH DERIVATIVES OF BETULIN | GLAXOSMITHKLINE LLC | 2017-09-07 | — | — | US | disclosed |
| US-20160120878-A1 | DERIVATIVES OF BETULIN | GLAXOSMITHKLINE LLC | 2016-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170252356-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING HIV WITH DERIVATIVES OF BETULIN | BET1, PGGT1B, TMPO | SLC10A1 156/4885CA9 3227/4885CA1 4420/4885 |
| US-20170348324-A1 | DERIVATIVES OF BETULIN | BET1, TMPO, PGGT1B | SLC10A1 112/4885CA9 3476/4885CA1 4200/4885 |
| US-20160120878-A1 | DERIVATIVES OF BETULIN | BET1, PGGT1B, TMPO | SLC10A1 113/4885CA9 3642/4885CA1 4302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.