SCHEMBL177190

SCHEMBL177190

CCCCCCCCc1ccc(CN)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.76
ESR1 P03372 2/20 0.63
ADRA2A P08913 2/20 0.63
ADORA3 P0DMS8 2/20 0.63
TACR2 P21452 2/20 0.63
SLC6A2 P23975 2/20 0.63
SLC6A4 P31645 2/20 0.63
SLC6A3 Q01959 2/20 0.63
KDM4E B2RXH2 1/20 0.63
ALDH1A1 P00352 1/20 0.63
LMNA P02545 1/20 0.63
SHBG P04278 1/20 0.63
TP53 P04637 1/20 0.63
CYP3A4 P08684 1/20 0.63
HSPD1 P10809 1/20 0.63
ADRB3 P13945 1/20 0.63
HTR2C P28335 1/20 0.63
HSPE1 P61604 1/20 0.63
HIF1A Q16665 1/20 0.63
TST Q16762 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4091747 1.00 HTR2A (0.76) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL393623 1.00 HTR2A (0.76) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL29285307 1.00 HTR2A (0.76) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL2674306 1.00 HTR2A (0.76) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL395308 1.00 HTR2A (0.76) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL394553 1.00 HTR2A (0.76) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL920406 1.00 HTR2A (0.76) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL29038707 1.00 HTR2A (0.76) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL395434 0.98 HTR2A (0.72) HTR2AESR1ADRA2AADORA3TACR2
Hydrochloric Acid SCHEMBL1856278 0.95 HTR2A (0.69) HTR2AESR1ADRA2AADORA3TACR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119570499-A Amphoteric surfactant and preparation method and application thereof 上海发凯化工有限公司 2025-03-07 CN disclosed
EP-2688911-B1 Biomarker discovery in complex biological fluid using bead or particle based libraries OPKO PHARMACEUTICALS LLC (US) 2017-08-02 EP disclosed
US-9707205-B2 S1P receptors modulators and their use thereof AKAAL PHARMA PTY LTD. (AU) 2017-07-18 US disclosed
CN-103732632-B Method for producing olefin block polymer using Group 4 transition metal complex 住友化学株式会社 2017-07-07 CN disclosed
US-9695260-B2 Method for producing olefin block polymer using plurality of types of transition metal catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-04 US disclosed
US-9688668-B2 Long chain base sphingosine kinase inhibitors UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2017-06-27 US disclosed
US-9688668-B2 Long chain base sphingosine kinase inhibitors UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2017-06-27 US disclosed
US-9593194-B2 Method for producing olefin block polymer using group 4 transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-03-14 US disclosed
EP-2657214-B1 PROCESS FOR PRODUCTION OF AROMATIC ALCOHOL OR HETEROCYCLIC AROMATIC ALCOHOL MITSUBISHI GAS CHEMICAL CO (JP) 2017-02-15 EP disclosed
EP-2344484-B1 S1P RECEPTORS MODULATORS AND USE THEREOF AKAAL PHARMA PTY LTD (AU) 2016-06-08 EP disclosed
EP-0588060-A2 Method for preparing aromatic secondary amino compound MITSUI TOATSU CHEMICALS, Inc. (JP) 1994-03-23 EP disclosed
US-4377690-A ENOLATES, USEFUL IN PREPARING LIGHT STABILIZERS CIBA-GEIGY CORPORATION (US) 1983-03-22 US disclosed
US-4263202-A PHOTOSTABILIZERS FOR PLASTICS USING METAL PHENOLATES CIBA-GEIGY CORPORATION (US) 1981-04-21 US disclosed
US-4234723-A COMPLEXES WITH HYDROXYBENZOATE ANIONS AND AMINE LIGANDS, PHOTOSTABILITY CIBA-GEIGY CORPORATION (US) 1980-11-18 US disclosed
US-4231921-A COMPLEX OF A METAL WITH PIPERIDINE WITH ONE ENOLATE GROUP, POLYMERS CIBA-GEIGY CORPORATION (US) 1980-11-04 US disclosed
US-4186267-A LIGHT STABILIZERS FOR POLYOLEFINS CIBA-GEIGY CORPORATION (US) 1980-01-29 US disclosed
EP-0000700-A1 Metal complexes with a chelating anion comprising a phenolate group, their preparation and their use as light stabilizers, especially for polymeric substances CIBA-GEIGY AG (CH) 1979-02-21 EP disclosed
EP-0000487-A1 Compounds containing enol groups, metal chelates made therefrom, their preparation and use as light stabilizers, especially for polymeric substances. CIBA-GEIGY AG (CH) 1979-02-07 EP disclosed
US-4046788-A ORTHO- OR PARA-HYDROXYBENZOATE ANIONS, AMINE LIGAND CIBA-GEIGY CORPORATION (US) 1977-09-06 US disclosed
US-3948852-A Nickel stabilisers for synthetic polymers CIBA-GEIGY CORPORATION (US) 1976-04-06 US disclosed