SCHEMBL395434

SCHEMBL395434

CCCCCc1ccc(CN)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.72
ESR1 P03372 2/20 0.59
ADRA2A P08913 2/20 0.59
ADORA3 P0DMS8 2/20 0.59
TACR2 P21452 2/20 0.59
SLC6A2 P23975 2/20 0.59
SLC6A4 P31645 2/20 0.59
SLC6A3 Q01959 2/20 0.59
ALDH1A1 P00352 2/20 0.59
KDM4E B2RXH2 1/20 0.59
LMNA P02545 1/20 0.59
SHBG P04278 1/20 0.59
TP53 P04637 1/20 0.59
CYP3A4 P08684 1/20 0.59
HSPD1 P10809 1/20 0.59
ADRB3 P13945 1/20 0.59
HTR2C P28335 1/20 0.59
HSPE1 P61604 1/20 0.59
HIF1A Q16665 1/20 0.59
TST Q16762 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29285307 0.98 HTR2A (0.76) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL177190 0.98 HTR2A (0.76) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL394553 0.98 HTR2A (0.76) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL395308 0.98 HTR2A (0.76) HTR2AESR1ADRA2AADORA3TACR2
Hydrochloric Acid SCHEMBL1856278 0.98 HTR2A (0.69) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL920406 0.98 HTR2A (0.76) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL29038707 0.98 HTR2A (0.76) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL393623 0.98 HTR2A (0.76) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL2674306 0.98 HTR2A (0.76) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL4091747 0.98 HTR2A (0.76) HTR2AESR1ADRA2AADORA3TACR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112624930-A Preparation method of 2, 2-bis (4-aminophenyl) hexafluoropropane 上海如鲲新材料有限公司 2021-04-09 CN claimed
US-20170305859-A1 An Anticonvulsant Compound ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE (GB) 2017-10-26 US claimed
EP-3191088-A1 AN ANTICONVULSANT COMPOUND Royal Holloway And Bedford New College (GB) 2017-07-19 EP claimed
WO-2016038379-A1 AN ANTICONVULSANT COMPOUND ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE (GB) 2016-03-17 WO claimed
EP-4741405-A1 ENHANCED PEROVSKITE MATERIALS FOR PHOTOVOLTAIC DEVICES CubicPV Inc. (US) 2026-05-13 EP disclosed
EP-3883940-B1 ENHANCED PEROVSKITE MATERIALS FOR PHOTOVOLTAIC DEVICES CUBICPV INC (US) 2026-04-22 EP disclosed
US-12540228-B2 Cross linked surface coating and interfacial layer for a perovskite material photovoltaic device CUBICPV INC. (US) 2026-02-03 US disclosed
US-12486235-B2 Metal oxide nanoparticle with alkylsiloxane ligands bonded thereto CUBICPV INC. (US) 2025-12-02 US disclosed
EP-3883939-B1 ENHANCED PEROVSKITE MATERIALS FOR PHOTOVOLTAIC DEVICES CUBICPV INC (US) 2025-11-26 EP disclosed
US-12300485-B2 Enhanced perovskite materials for photovoltaic devices CubivPV Inc. (US) 2025-05-13 US disclosed
US-12243740-B2 Enhanced perovskite materials for photovoltaic devices CUBICPV INC. (US) 2025-03-04 US disclosed
CN-119136633-A Enhanced perovskite materials for photovoltaic devices 立方光伏股份有限公司 2024-12-13 CN disclosed
US-20030144338-A1 Tyrosine phosphatase inhibitors TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2003-07-31 US disclosed
US-20030069127-A1 Modified particle,support, catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMTED (JP) 2003-04-10 US disclosed
EP-1300425-A2 Catalyst component for addition polymerization, process for producing said catalyst and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-04-09 EP disclosed
US-20030060579-A1 Catalyst component for addition polymerization, process for producing catalyst for addition polymerization and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-03-27 US disclosed
EP-1284260-A1 TYROSINE PHOSPHATASE INHIBITORS Takeda Chemical Industries, Ltd. (JP) 2003-02-19 EP disclosed
US-20020143124-A1 Homogeneous type solid catalyst component or homogeneous type solid catalyst, process for production thereof and process for producing addition polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-10-03 US disclosed
EP-1113026-A2 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-04 EP disclosed
CN-1069976-A Hexanaphthene and tetrahydropyran derivatives HOFFMANN LA ROCHE (CH) 1993-03-17 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030144338-A1 Tyrosine phosphatase inhibitors PTPRC, PTPN1, PTPRM HTR2A 4225/4885ESR1 3084/4885ADRA2A 4316/4885
US-12540228-B2 Cross linked surface coating and interfacial layer for a perovskite material photovoltaic device HCN2, HCN1, BRSK1 HTR2A 1228/4885ESR1 1630/4885ADRA2A 1793/4885
US-12300485-B2 Enhanced perovskite materials for photovoltaic devices ZFX, KCNH1, CXXC4 HTR2A 1794/4885ESR1 2776/4885ADRA2A 1416/4885
US-12486235-B2 Metal oxide nanoparticle with alkylsiloxane ligands bonded thereto MACO1, CD4, ITGAV HTR2A 3513/4885ESR1 780/4885ADRA2A 2554/4885
US-20170305859-A1 An Anticonvulsant Compound PSEN2, BACE2, APP HTR2A 551/4885ESR1 4234/4885ADRA2A 1121/4885
US-12243740-B2 Enhanced perovskite materials for photovoltaic devices ZFX, ZYX, CXXC5 HTR2A 1341/4885ESR1 2323/4885ADRA2A 1847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.