Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.76 |
| ▸ | ESR1 | P03372 | 2/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.63 |
| ▸ | TACR2 | P21452 | 2/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | SHBG | P04278 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.63 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.63 |
| ▸ | HTR2C | P28335 | 1/20 | 0.63 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | TST | Q16762 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4091747 | 1.00 | HTR2A (0.76) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL393623 | 1.00 | HTR2A (0.76) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL29285307 | 1.00 | HTR2A (0.76) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL177190 | 1.00 | HTR2A (0.76) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL395308 | 1.00 | HTR2A (0.76) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL394553 | 1.00 | HTR2A (0.76) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL920406 | 1.00 | HTR2A (0.76) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL29038707 | 1.00 | HTR2A (0.76) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL395434 | 0.98 | HTR2A (0.72) | HTR2AESR1ADRA2AADORA3TACR2 | |
| Hydrochloric Acid SCHEMBL1856278 | 0.95 | HTR2A (0.69) | HTR2AESR1ADRA2AADORA3TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12037541-B2 | Anionic-cationic-nonionic surfactant, production and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2024-07-16 | — | — | US | disclosed |
| US-20220033705-A1 | ANIONIC-CATIONIC-NONIONIC SURFACTANT, PRODUCTION AND USE THEREOF | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2022-02-03 | — | — | US | disclosed |
| US-11186764-B2 | Anionic-cationic-nonionic surfactant, production and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2021-11-30 | — | — | US | disclosed |
| US-20190330516-A1 | ANIONIC-CATIONIC-NONIONIC SURFACTANT, PRODUCTION AND USE THEREOF | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2019-10-31 | — | — | US | disclosed |
| US-10400156-B2 | Anionic-cationic-nonionic surfactant, production and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2019-09-03 | — | — | US | disclosed |
| CN-105642185-B | A kind of anionic-cationic-nonionic surface active agent, its manufacturing method and its application | 中国石油化工股份有限公司 | 2018-07-31 | — | — | CN | disclosed |
| US-20170313928-A1 | ANIONIC-CATIONIC-NONIONIC SURFACTANT,PRODUCTION AND USE THEREOF | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2017-11-02 | — | — | US | disclosed |
| US-9770442-B2 | Self-assembling amphiphilic polymers as anti-cancer agents | ALLEXCEL INC. (US) | 2017-09-26 | — | — | US | disclosed |
| EP-2167103-B1 | SELF-ASSEMBLING AMPHIPHILIC POLYMERS AS ANTICANCER AGENTS | ALLEXCEL INC (US) | 2017-03-01 | — | — | EP | disclosed |
| EP-2120974-B1 | SELF-ASSEMBLING AMPHIPHILIC POLYMERS AS ANTIVIRAL AGENTS | ALLEXCEL INC (US) | 2017-03-01 | — | — | EP | disclosed |
| WO-2006043149-A2 | NOVEL DICARBOXYLIC ACID DERIVATIVES | BIOPROJET (FR) | 2006-04-27 | — | — | WO | disclosed |
| EP-1650186-A1 | Novel dicarboxylic acid derivatives | BIOPROJET (FR) | 2006-04-26 | — | — | EP | disclosed |
| EP-1470137-A4 | EDG RECEPTOR AGONISTS | MERCK & CO INC (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20050070506-A1 | Selective s1p1/edg1 receptor agonists | DOHERTY GEORGE A (US) | 2005-03-31 | — | — | US | disclosed |
| US-20050033055-A1 | Edg receptor agonists | MERCK SHARP & DOHME CORP. | 2005-02-10 | — | — | US | disclosed |
| EP-1469863-A2 | SELECTIVE S1P1/EDG1 RECEPTOR AGONISTS | Merck & Co., Inc. (US) | 2004-10-27 | — | — | EP | disclosed |
| EP-1470137-A1 | EDG RECEPTOR AGONISTS | Merck & Co., Inc. (US) | 2004-10-27 | — | — | EP | disclosed |
| US-20040058894-A1 | Selective S1P1/Edg1 receptor agonists | DOHERTY GEORGE A (US) | 2004-03-25 | — | — | US | disclosed |
| WO-2003061567-A2 | SELECTIVE S1P1/EDG1 RECEPTOR AGONISTS | MERCK & CO., INC. (US) | 2003-07-31 | — | — | WO | disclosed |
| WO-2003062252-A1 | EDG RECEPTOR AGONISTS | MERCK & CO., INC. (US) | 2003-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070506-A1 | Selective s1p1/edg1 receptor agonists | S1PR1, S1PR3, S1PR5 | HTR2A 1401/4885ESR1 911/4885ADRA2A 331/4885 |
| US-20040058894-A1 | Selective S1P1/Edg1 receptor agonists | S1PR1, S1PR3, S1PR2 | HTR2A 857/4885ESR1 820/4885ADRA2A 306/4885 |
| US-20190330516-A1 | ANIONIC-CATIONIC-NONIONIC SURFACTANT, PRODUCTION AND USE THEREOF | LIPA, ABHD12, ABHD16A | HTR2A 4056/4885ESR1 2837/4885ADRA2A 2849/4885 |
| US-20050033055-A1 | Edg receptor agonists | EDNRA, EDNRB, GPR65 | HTR2A 585/4885ESR1 220/4885ADRA2A 128/4885 |
| US-12037541-B2 | Anionic-cationic-nonionic surfactant, production and use thereof | LIPA, SGMS1, AQP1 | HTR2A 3835/4885ESR1 2274/4885ADRA2A 2633/4885 |
| US-11186764-B2 | Anionic-cationic-nonionic surfactant, production and use thereof | LIPA, ABHD12, ABHD16A | HTR2A 4056/4885ESR1 2837/4885ADRA2A 2849/4885 |
| US-20220033705-A1 | ANIONIC-CATIONIC-NONIONIC SURFACTANT, PRODUCTION AND USE THEREOF | LIPA, ABHD16A, ABHD12 | HTR2A 3827/4885ESR1 2216/4885ADRA2A 2736/4885 |
| US-10400156-B2 | Anionic-cationic-nonionic surfactant, production and use thereof | LIPA, ABHD12, ABHD16A | HTR2A 4056/4885ESR1 2837/4885ADRA2A 2849/4885 |
| US-20170313928-A1 | ANIONIC-CATIONIC-NONIONIC SURFACTANT,PRODUCTION AND USE THEREOF | LIPA, ABHD12, ABHD16A | HTR2A 4056/4885ESR1 2837/4885ADRA2A 2849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.