Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29483472 | 1.00 | HDAC1 (0.65) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL12679023 | 0.92 | HDAC1 (0.69) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL29571652 | 0.90 | ALDH1A1 (0.58) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL15447287 | 0.90 | ALDH1A1 (0.58) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL12679041 | 0.87 | HDAC1 (0.64) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL1461825 | 0.87 | HDAC1 (0.63) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL29483474 | 0.87 | HDAC1 (0.63) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL29483480 | 0.86 | HDAC1 (0.63) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL4357989 | 0.86 | HDAC1 (0.63) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL11784819 | 0.84 | HDAC1 (0.61) | HDAC1HDAC6HDAC3HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812060-B | Arylation method of tetrahydroquinoline | 绍兴文理学院 | 2022-04-29 | — | — | CN | disclosed |
| CN-112812060-A | Arylation method of tetrahydroquinoline | 绍兴文理学院 | 2021-05-18 | — | — | CN | disclosed |
| CN-102066337-A | 5-hydroxypyrimidine-4-carboxamide compounds | DAIICHI SANKYO CO LTD | 2011-05-18 | — | — | CN | disclosed |
| US-20110112103-A1 | 5-HYDROXYPYRIMIDINE-4-CARBOXAMIDE COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112103-A1 | 5-HYDROXYPYRIMIDINE-4-CARBOXAMIDE COMPOUND | EPOR, CBR1, CBR3 | HDAC1 570/4885HDAC6 1531/4885HDAC3 564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.