Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.70 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | NOS1 | P29475 | 5/20 | 0.59 |
| ▸ | METAP2 | P50579 | 3/20 | 0.59 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.59 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.57 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.53 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29559746 | 1.00 | MAPT (1.00) | MAPTKDM4EMEN1KMT2APKM | |
| Bromide SCHEMBL2931157 | 0.98 | MAPT (0.96) | MAPTKDM4EMEN1KMT2APKM | |
| Hydrochloric Acid SCHEMBL2925515 | 0.98 | MAPT (0.96) | MAPTKDM4EMEN1KMT2APKM | |
| Hydrochloric Acid SCHEMBL3871258 | 0.98 | MAPT (0.96) | MAPTKDM4EMEN1KMT2APKM | |
| Bromide SCHEMBL2933643 | 0.98 | MAPT (0.96) | MAPTKDM4EMEN1KMT2APKM | |
| SCHEMBL28140797 | 0.88 | MAPT (0.77) | MAPTKDM4EMEN1KMT2APKM | |
| SCHEMBL7210882 | 0.85 | MEN1 (0.72) | MAPTKDM4EMEN1KMT2APKM | |
| SCHEMBL6199433 | 0.83 | MAPT (0.70) | MAPTKDM4EMEN1KMT2APKM | |
| SCHEMBL8003451 | 0.83 | MAPT (0.70) | MAPTKDM4EMEN1KMT2APKM | |
| SCHEMBL117208 | 0.83 | ROCK2 (1.00) | MAPTKDM4EMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2140 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215863-B | Preparation method of medical intermediate 6, 9-dihydro-1H-pyrazolo [3,4-f ] quinoline-8-nitrile derivative | 南京欣久医药科技有限公司 | 2024-12-10 | — | — | CN | claimed |
| CN-114456755-B | Epoxy resin composition, preparation method and application thereof | 江苏中科科化新材料股份有限公司 | 2024-03-12 | — | — | CN | claimed |
| CN-117250833-A | Semiconductor chip photoresist cleaning solution, preparation method and application thereof | 浙江奥首材料科技有限公司 | 2023-12-19 | — | — | CN | claimed |
| CN-116332943-A | Preparation method of drug intermediate disubstituted 1,6-dihydropyrrolo [2,3-g ] indazole derivative | 南京苏亦欣医药科技有限公司 | 2023-06-27 | — | — | CN | claimed |
| WO-2022271840-A1 | SELECTIVE INDAZOLE LRRK2 INHIBITORS AND METHODS FOR USE THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-12-29 | — | — | WO | claimed |
| CN-115504937-A | Method for synthesizing axitinib intermediate 6-aminoindazole by tubular reactor | 喆鹿(山东)新材料有限公司 | 2022-12-23 | — | — | CN | claimed |
| CN-114457373-B | Preparation method and application of monatomic material with Ni-N2+2 stereo configuration active sites | 大连理工大学 | 2022-12-20 | — | — | CN | claimed |
| CN-115215863-A | Preparation method of pharmaceutical intermediate 6,9-dihydro-1H-pyrazolo [3,4-f ] quinoline-8-nitrile derivative | 南京欣久医药科技有限公司 | 2022-10-21 | — | — | CN | claimed |
| CN-115141181-A | Novel small molecule compound and preparation method and application thereof | 温州医科大学 | 2022-10-04 | — | — | CN | claimed |
| CN-114457373-A | Preparation method and application of monatomic material with Ni-N2+2 steric configuration active sites | 大连理工大学 | 2022-05-10 | — | — | CN | claimed |
| EP-0904769-A1 | Keratin fibre dye compositions containing Indazole amine derivatives and dyeing method | L'OREAL (FR) | 1999-03-31 | — | — | EP | claimed |
| US-5657064-A | Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds | XEROX CORPORATION (US) | 1997-08-12 | — | — | US | claimed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0743574-A2 | Migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| EP-0673782-A2 | Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds | XEROX CORPORATION (US) | 1995-09-27 | — | — | EP | claimed |
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | claimed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | claimed |
| EP-0299533-A2 | High potency sweetening agents | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | claimed |