Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 9/20 | 0.52 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17730114 | 0.86 | DGAT1 (0.60) | DGAT1SOAT1USP30ALDH1A1MAPT | |
| SCHEMBL20838730 | 0.86 | DGAT1 (0.60) | DGAT1SOAT1USP30ALDH1A1MAPT | |
| SCHEMBL18763690 | 0.85 | DGAT1 (0.51) | DGAT1USP30ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL17327303 | 0.85 | DGAT1 (0.51) | DGAT1USP30ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL17731429 | 0.83 | HTR2C (0.54) | USP30ALDH1A1DRD2 | |
| SCHEMBL17729966 | 0.81 | ALDH1A1 (0.48) | DGAT1CYP2C9USP30ALDH1A1MAPT | |
| SCHEMBL17730056 | 0.81 | DGAT1 (0.46) | DGAT1CYP2C9USP30ALDH1A1MAPT | |
| SCHEMBL17737051 | 0.80 | EPHX2 (0.73) | DGAT1ALDH1A1MAPTSMN1; SMN2EPHX2 | |
| SCHEMBL20838672 | 0.80 | EPHX2 (0.73) | DGAT1ALDH1A1MAPTSMN1; SMN2EPHX2 | |
| SCHEMBL17737372 | 0.80 | EPHX2 (0.73) | DGAT1ALDH1A1MAPTSMN1; SMN2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3215141-A2 | IMMUNOREGULATORY AGENTS | Flexus Biosciences, Inc. (US) | 2017-09-13 | — | — | EP | disclosed |
| WO-2016073738-A2 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES, INC. (US) | 2016-05-12 | — | — | WO | disclosed |