Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ALKBH1 | Q13686 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1773823 | 0.91 | AOC3 (0.42) | ALKBH1SCN9AKDM4ELMNATSHR | |
| SCHEMBL1772995 | 0.90 | CHRM4 (0.42) | CHRM4CHRM5CHRM1CHRM3ALKBH1 | |
| SCHEMBL1772364 | 0.90 | CHRM4 (0.42) | CHRM4LMNATSHRALDH1A1MAPT | |
| SCHEMBL12002658 | 0.88 | SLC6A2 (0.44) | KDM4ELMNAALDH1A1MAPTPTGER1 | |
| SCHEMBL1773145 | 0.87 | MAPT (0.39) | KDM4ETSHRALDH1A1MAPTL3MBTL1 | |
| SCHEMBL1772472 | 0.86 | CHRM4 (0.40) | CHRM4CHRM5CHRM1CHRM3SCN9A | |
| SCHEMBL12602088 | 0.86 | CHRM4 (0.43) | CHRM4CHRM5CHRM1CHRM3SCN9A | |
| Hydrochloric Acid SCHEMBL1773577 | 0.84 | ME3 (0.42) | KDM4EALDH1A1MAPT | |
| SCHEMBL1774023 | 0.81 | AOC3 (0.42) | AOC3 | |
| SCHEMBL1772041 | 0.81 | HRH3 (0.41) | SCN9AKDM4EALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110112103-A1 | 5-HYDROXYPYRIMIDINE-4-CARBOXAMIDE COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112103-A1 | 5-HYDROXYPYRIMIDINE-4-CARBOXAMIDE COMPOUND | EPOR, CBR1, CBR3 | CHRM4 1650/4885CHRM5 1449/4885CHRM1 710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.