Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1773577 | 0.94 | ME3 (0.42) | MAPTALDH1A1KDM4EMALT1GRIN2B | |
| SCHEMBL12002658 | 0.93 | SLC6A2 (0.44) | MAPTALDH1A1F10KDM4ESLC6A2 | |
| SCHEMBL1772041 | 0.92 | HRH3 (0.41) | MAPTALDH1A1L3MBTL1KDM4ESLC6A2 | |
| SCHEMBL12002461 | 0.91 | CKS1B (0.38) | MAPTALDH1A1KDM4EMALT1 | |
| SCHEMBL1772899 | 0.90 | MAPT (0.42) | MAPTALDH1A1F10KDM4EMALT1 | |
| SCHEMBL1773015 | 0.89 | F10 (0.39) | MAPTALDH1A1F10SLC6A2SLC6A4 | |
| SCHEMBL1773978 | 0.89 | GPR119 (0.41) | MAPTF10 | |
| SCHEMBL1773444 | 0.88 | MAPT (0.39) | MAPTKDM4EMALT1 | |
| SCHEMBL1773823 | 0.87 | AOC3 (0.42) | MAPTALDH1A1KDM4ETSHR | |
| SCHEMBL1773209 | 0.87 | CHRM4 (0.44) | MAPTALDH1A1L3MBTL1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110112103-A1 | 5-HYDROXYPYRIMIDINE-4-CARBOXAMIDE COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112103-A1 | 5-HYDROXYPYRIMIDINE-4-CARBOXAMIDE COMPOUND | EPOR, CBR1, CBR3 | MAPT 4845/4885ALDH1A1 1179/4885F10 534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.