Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 20/20 | 0.66 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17732402 | 1.00 | CYP11B2 (0.66) | CYP11B2CYP11B1 | |
| Vicadrostat SCHEMBL17465823 | 0.91 | CYP11B2 (0.64) | CYP11B2CYP11B1 | |
| Vicadrostat SCHEMBL17456323 | 0.91 | CYP11B2 (0.64) | CYP11B2CYP11B1 | |
| Vicadrostat SCHEMBL17456267 | 0.91 | CYP11B2 (0.64) | CYP11B2CYP11B1 | |
| SCHEMBL17456321 | 0.91 | CYP11B2 (0.64) | CYP11B2CYP11B1 | |
| SCHEMBL17732406 | 0.89 | CYP11B2 (0.65) | CYP11B2CYP11B1 | |
| SCHEMBL17456270 | 0.88 | CYP11B2 (0.70) | CYP11B2CYP11B1 | |
| SCHEMBL17732404 | 0.88 | CYP11B2 (0.61) | CYP11B2CYP11B1 | |
| SCHEMBL31307589 | 0.86 | CYP11B2 (0.58) | CYP11B2CYP11B1 | |
| SCHEMBL17456263 | 0.86 | CYP11B2 (0.58) | CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9334285-B2 | Aldosterone synthase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-05-10 | — | — | US | disclosed |