Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 20/20 | 0.58 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17456263 | 1.00 | CYP11B2 (0.58) | CYP11B2CYP11B1 | |
| SCHEMBL25584199 | 0.90 | CYP11B2 (0.58) | CYP11B2CYP11B1 | |
| Vicadrostat SCHEMBL17456323 | 0.87 | CYP11B2 (0.64) | CYP11B2CYP11B1 | |
| Vicadrostat SCHEMBL17465823 | 0.87 | CYP11B2 (0.64) | CYP11B2CYP11B1 | |
| Vicadrostat SCHEMBL17456267 | 0.87 | CYP11B2 (0.64) | CYP11B2CYP11B1 | |
| SCHEMBL17732403 | 0.86 | CYP11B2 (0.66) | CYP11B2CYP11B1 | |
| SCHEMBL17732402 | 0.86 | CYP11B2 (0.66) | CYP11B2CYP11B1 | |
| SCHEMBL17456321 | 0.86 | CYP11B2 (0.64) | CYP11B2CYP11B1 | |
| SCHEMBL25584394 | 0.83 | CYP11B2 (0.41) | CYP11B2CYP11B1 | |
| SCHEMBL17456320 | 0.83 | CYP11B2 (0.66) | CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12263157-B2 | Aldosterone synthase inhibitors for treating chronic kidney disease | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2025-04-01 | — | — | US | disclosed |
| US-20250049763-A1 | ALDOSTERONE SYNTHASE INHIBITORS FOR TREATING CHRONIC KIDNEY DISEASE | BOEHRINGER INGELHEIM INT (DE) | 2025-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250049763-A1 | ALDOSTERONE SYNTHASE INHIBITORS FOR TREATING CHRONIC KIDNEY DISEASE | SLC5A2, SLC5A1, REN | CYP11B2 10/4885CYP11B1 19/4885 |
| US-12263157-B2 | Aldosterone synthase inhibitors for treating chronic kidney disease | SLC5A1, SLC5A2, REN | CYP11B2 12/4885CYP11B1 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.