Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257418 | 0.89 | RORC (0.34) | RORC | |
| SCHEMBL11897352 | 0.86 | SLC22A12 (0.35) | SLC16A3SLC22A12ELANEHIF1A | |
| SCHEMBL177258 | 0.85 | ELANE (0.35) | SLC16A3SLC22A12ELANE | |
| SCHEMBL178183 | 0.84 | SLC22A12 (0.36) | SLC22A12 | |
| SCHEMBL176949 | 0.84 | SLC22A12 (0.38) | SLC16A3SLC22A12ELANE | |
| SCHEMBL11897506 | 0.83 | CYP11B2 (0.36) | SLC22A12 | |
| SCHEMBL11897199 | 0.81 | CYP11B2 (0.33) | SLC16A3SLC22A12HIF1A | |
| SCHEMBL3339531 | 0.76 | MAP2K4 (0.34) | SLC16A3SLC22A12 | |
| SCHEMBL177174 | 0.75 | MAP2K4 (0.39) | RORCELANE | |
| SCHEMBL2238954 | 0.75 | SLC22A12 (0.35) | SLC16A3SLC22A12ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2345644-A1 | INDAZOLE COMPOUND | Asahi Kasei Pharma Corporation (JP) | 2011-07-20 | — | — | EP | disclosed |