Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.33 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.33 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734337 | 0.85 | SKP2 (0.56) | SKP2BACE1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL79106 | 0.80 | SKP2 (0.50) | SKP2CYP3A4CYP2D6CYP2C9IGF1R | |
| SCHEMBL9656290 | 0.80 | CNR1 (0.45) | SKP2BACE1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL15787340 | 0.80 | BACE1 (0.50) | SKP2BACE1TAAR1 | |
| SCHEMBL5498171 | 0.78 | TRPA1 (0.44) | BACE1CYP1A2TAAR1NPC1MAPK1 | |
| SCHEMBL169507 | 0.78 | TRPA1 (0.44) | BACE1CYP1A2TAAR1NPC1MAPK1 | |
| SCHEMBL11312772 | 0.77 | BACE1 (0.46) | SKP2BACE1 | |
| SCHEMBL11856257 | 0.76 | TAAR1 (0.41) | SKP2BACE1TAAR1 | |
| SCHEMBL18779988 | 0.76 | SIGMAR1 (0.45) | SKP2BACE1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13694253 | 0.76 | ATM (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168944-B1 | AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2016-05-11 | — | — | EP | disclosed |