SCHEMBL1773406

SCHEMBL1773406

N#Cc1ccc(-c2ccc(Br)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.64
MAOA P21397 1/20 0.64
MMP3 P08254 1/20 0.58
KIF11 P52732 3/20 0.52
CA12 O43570 2/20 0.48
CA2 P00918 2/20 0.48
CA9 Q16790 2/20 0.48
CA1 P00915 1/20 0.48
ALDH1A1 P00352 2/20 0.48
MAPK1 P28482 1/20 0.48
AHR P35869 2/20 0.47
IDO1 P14902 1/20 0.47
CYP11B2 P19099 1/20 0.47
CYP2A6 P11509 2/20 0.46
CA3 P07451 1/20 0.46
CA6 P23280 1/20 0.46
CA14 Q9ULX7 1/20 0.46
HDAC2 Q92769 1/20 0.44
ERBB2 P04626 1/20 0.44
TSHR P16473 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15496905 1.00 MAOB (0.64) MAOBMAOAMMP3KIF11CA12
SCHEMBL15679888 0.93 MAOB (0.57) MAOBMAOAMMP3KIF11CA12
SCHEMBL154636 0.92
Water SCHEMBL27994834 0.92 MAOB (0.73) MAOBMAOAMMP3CA12CA2
Hydrochloric Acid SCHEMBL30722972 0.89 MAOB (0.70) MAOBMAOAMMP3CA12CA2
SCHEMBL6827721 0.89 MAOB (0.70) MAOBMAOAMMP3CA12CA2
SCHEMBL14656590 0.89 MAOB (0.70) MAOBMAOAMMP3CA12CA2
SCHEMBL25546197 0.87 MAOB (0.52) MAOBMAOAMMP3KIF11CA12
SCHEMBL13063633 0.86 MMP3 (0.74) MAOBMAOAMMP3KIF11CA12
SCHEMBL396846 0.86 MMP3 (0.74) MAOBMAOAMMP3KIF11CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108178737-B 4 '- (4-bromonaphthalene-1-yl) [1, 1' -biphenyl ] -4-nitrile and synthesis method thereof 河南省科学院化学研究所有限公司 2020-06-19 CN claimed
US-RE50748-E1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2026-01-06 US disclosed
WO-2025121699-A1 HETEROARYL AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 랩토 2025-06-12 WO disclosed
WO-2025084253-A1 CARBAZOLE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2025-04-24 WO disclosed
CN-113527330-B Compound and application thereof 北京鼎材科技有限公司 2024-05-24 CN disclosed
WO-2024086246-A2 2-SUBSTITUTED 3,4 A, 5, 7, 8, 8 A-HEXAHYDRO-4H-THIOP YRANO [4,3- DJPYRIMIDIN-4-ONES FOR WOUND TREATMENT Eluciderm Inc. (US) 2024-04-25 WO disclosed
CN-117836291-A Cyano-substituted carbazole derivative and organic electroluminescent device comprising same 株式会社乐普拓 2024-04-05 CN disclosed
CN-112745318-B Compound and application thereof 北京鼎材科技有限公司 2024-03-19 CN disclosed
CN-112778300-B Organic compound and organic electroluminescent device containing the same 北京鼎材科技有限公司 2024-02-02 CN disclosed
US-20230320205-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-10-05 US disclosed
US-6306892-B1 ENZYME INHIBITORS HETEROCYCLIC AMIDES AGOURON PHARMACEUTICALS, INC. 2001-10-23 US disclosed
US-6174915-B1 FOR TREATING MAMMALIAN DISEASE CONDITION MEDIATED BY METALLOPROTEINASE ACTIVITY AGOURON PHARMACEUTICALS, INC. 2001-01-16 US disclosed
US-6008243-A AN ENZYME INHIBITOR FOR PREVENTING THE DEGRADATION AND REMODELING OF CONNECTIVE TISSUES AGOURON PHARMACEUTICALS, INC. (US) 1999-12-28 US disclosed
EP-0937042-A1 HETEROARYL SUCCINAMIDES AND THEIR USE AS METALLOPROTEINASE INHIBITORS AGOURON PHARMACEUTICALS, INC. (US) 1999-08-25 EP disclosed
WO-1998017643-A1 HETEROARYL SUCCINAMIDES AND THEIR USE AS METALLOPROTEINASE INHIBITORS AGOURON PHARMACEUTICALS, INC. (US) 1998-04-30 WO disclosed
EP-0637624-B1 Antiferroelectric liquid crystal compound SHOWA SHELL SEKIYU (JP) 1996-09-25 EP disclosed
US-5417885-A Antiferroelectric liquid crystal compound SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) 1995-05-23 US disclosed
EP-0637624-A1 Antiferroelectric liquid crystal compound Showa Shell Sekiyu Kabushiki Kaisha (JP) 1995-02-08 EP disclosed
US-4309539-A ELECTROOPTICS HOFFMANN-LA ROCHE INC. (US) 1982-01-05 US disclosed
US-4062798-A NEMATIC CRYSTALS HOFFMANN-LA ROCHE INC. (US) 1977-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230320205-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS NOM1, MNS1, NOS1 MAOB 846/4885MAOA 779/4885MMP3 4715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.