Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17735524 | 0.88 | TSHR (0.35) | TSHRTHRBOPRM1LMNA | |
| SCHEMBL25469958 | 0.83 | TSHR (0.32) | TSHRTHRBOPRM1LMNA | |
| SCHEMBL15914390 | 0.78 | TSHR (0.44) | TSHRTHRBDNM1OPRM1TRPM8 | |
| SCHEMBL31454128 | 0.78 | TSHR (0.44) | TSHRTHRBDNM1OPRM1TRPM8 | |
| Fluoride SCHEMBL28311558 | 0.76 | TSHR (0.42) | TSHRTHRBDNM1OPRM1TRPM8 | |
| SCHEMBL29401979 | 0.76 | TSHR (0.42) | TSHRTHRBDNM1OPRM1TRPM8 | |
| SCHEMBL14162085 | 0.76 | TSHR (0.42) | TSHRTHRBDNM1OPRM1TRPM8 | |
| SCHEMBL14162212 | 0.76 | TSHR (0.42) | TSHRTHRBDNM1OPRM1TRPM8 | |
| SCHEMBL18221763 | 0.74 | TSHR (0.40) | TSHRTHRBDNM1TRPM8MEN1 | |
| SCHEMBL17859369 | 0.74 | TSHR (0.40) | TSHRTHRBDNM1OPRM1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230255101-A1 | Tetradentate Metal Complexes with Carbon Group Bridging Ligands | UNIV ARIZONA STATE (US) | 2023-08-10 | — | — | US | disclosed |
| US-11653560-B2 | Tetradentate metal complexes with carbon group bridging ligands | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2023-05-16 | — | — | US | disclosed |
| US-10033003-B2 | Tetradentate metal complexes with carbon group bridging ligands | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-07-24 | — | — | US | disclosed |
| US-20160133862-A1 | TETRADENTATE METAL COMPLEXES WITH CARBON GROUP BRIDGING LIGANDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2016-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160133862-A1 | TETRADENTATE METAL COMPLEXES WITH CARBON GROUP BRIDGING LIGANDS | STAU1, POLR1G, CLTC | TSHR 863/4885THRB 2315/4885DNM1 735/4885 |
| US-10033003-B2 | Tetradentate metal complexes with carbon group bridging ligands | STAU1, POLR1G, CLTC | TSHR 863/4885THRB 2315/4885DNM1 735/4885 |
| US-20230255101-A1 | Tetradentate Metal Complexes with Carbon Group Bridging Ligands | STAU1, POLR1G, CLTC | TSHR 863/4885THRB 2315/4885DNM1 735/4885 |
| US-11653560-B2 | Tetradentate metal complexes with carbon group bridging ligands | PDCD2L, STAU1, POLR1G | TSHR 719/4885THRB 1905/4885DNM1 1506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.