SCHEMBL17735781

SCHEMBL17735781

c1ccc(-n2c3ccccc3c3cc(-c4ccc(-n5c6ccc(-c7cccc8c7oc7ccccc78)cc6c6cc(-c7cccc8c7sc7ccccc78)ccc65)cc4)ccc32)cc1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.42
PRKDC P78527 11/20 0.39
PIK3CD O00329 2/20 0.36
PIK3CB P42338 2/20 0.36
BRD4 O60885 1/20 0.36
PIK3CA P42336 1/20 0.36
MTOR P42345 1/20 0.36
PIK3CG P48736 1/20 0.36
KCNH2 Q12809 1/20 0.36
BRDT Q58F21 1/20 0.36
KDM4E B2RXH2 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
GGPS1 O95749 1/20 0.33
PTGES2 Q9H7Z7 1/20 0.32
PRMT5 O14744 1/20 0.30
WDR77 Q9BQA1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12158911 0.95 ALOX5 (0.41) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL18505097 0.94 ALOX5 (0.40) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL18505094 0.94 ALOX5 (0.40) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL20232131 0.94 ALOX5 (0.43) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL20715247 0.94 ALOX5 (0.42) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL20715250 0.94 ALOX5 (0.42) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL24164383 0.92 ALOX5 (0.43) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL16864298 0.92 ALOX5 (0.36) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL20715108 0.91 ALOX5 (0.41) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL22131303 0.91 ALOX5 (0.39) ALOX5PRKDCPIK3CDPIK3CBBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727419-B2 Organic light emitting display device LG DISPLAY CO., LTD. (KR) 2020-07-28 US disclosed
US-20160133855-A1 ORGANIC LIGHT EMITTING DISPLAY DEVICE LG DISPLAY CO., LTD. (KR) 2016-05-12 US disclosed
US-20160133855-A1 ORGANIC LIGHT EMITTING DISPLAY DEVICE LG DISPLAY CO., LTD. (KR) 2016-05-12 US disclosed