Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.43 |
| ▸ | PRKDC | P78527 | 11/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.37 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.34 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12158911 | 0.97 | ALOX5 (0.41) | ALOX5PRKDCPIK3CDPIK3CBBRD4 | |
| SCHEMBL18505094 | 0.94 | ALOX5 (0.40) | ALOX5PRKDCPIK3CDPIK3CBBRD4 | |
| SCHEMBL18505097 | 0.94 | ALOX5 (0.40) | ALOX5PRKDCPIK3CDPIK3CBBRD4 | |
| SCHEMBL17735781 | 0.94 | ALOX5 (0.42) | ALOX5PRKDCPIK3CDPIK3CBBRD4 | |
| SCHEMBL20715247 | 0.94 | ALOX5 (0.42) | ALOX5PRKDCPIK3CDPIK3CBBRD4 | |
| SCHEMBL20715250 | 0.94 | ALOX5 (0.42) | ALOX5PRKDCPIK3CDPIK3CBBRD4 | |
| SCHEMBL17735780 | 0.91 | ALOX5 (0.39) | ALOX5PRKDCPIK3CDPIK3CBBRD4 | |
| SCHEMBL18505102 | 0.91 | ALOX5 (0.40) | ALOX5PRKDCPIK3CDPIK3CBBRD4 | |
| SCHEMBL18505095 | 0.91 | ALOX5 (0.40) | ALOX5PRKDCPIK3CDPIK3CBBRD4 | |
| SCHEMBL24676300 | 0.90 | ALOX5 (0.41) | ALOX5PRKDCPIK3CDPIK3CBBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3548481-B1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-08-23 | — | — | EP | disclosed |
| US-11329233-B2 | Heterocyclic compounds for use in electronic devices | MERCK PATENT GMBH (DE) | 2022-05-10 | — | — | US | disclosed |
| US-20190296250-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-09-26 | — | — | US | disclosed |
| WO-2018100029-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190296250-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | NQO1, DDT, ETV6 | ALOX5 1459/4885PRKDC 1678/4885PIK3CD 3277/4885 |
| US-11329233-B2 | Heterocyclic compounds for use in electronic devices | NQO1, DDT, ETV6 | ALOX5 1459/4885PRKDC 1678/4885PIK3CD 3277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.