SCHEMBL17736739

SCHEMBL17736739

CN1CC(O)N(c2cc(C(C)(C)F)on2)C1=O

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 1/20 0.41
ALOX15 P16050 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 1/20 0.34
MMP1 P03956 1/20 0.31
MMP14 P50281 1/20 0.31
ADAMTS5 Q9UNA0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11074634 0.92 HTR7 (0.39) HTR7ALOX15MEN1KMT2AALDH1A1
SCHEMBL17736829 0.91 HTR7 (0.39) HTR7ALOX15MEN1KMT2AALDH1A1
SCHEMBL8378260 0.91 HTR7 (0.47) HTR7ALOX15MEN1KMT2AALDH1A1
SCHEMBL17736995 0.90 HTR7 (0.39) HTR7ALOX15MEN1KMT2AALDH1A1
SCHEMBL11304777 0.88 HTR7 (0.38) HTR7ALOX15MEN1KMT2AALDH1A1
SCHEMBL11298417 0.86 HTR7 (0.37) HTR7ALOX15MEN1KMT2AALDH1A1
SCHEMBL11295363 0.86 HTR7 (0.37) HTR7ALOX15MEN1KMT2AALDH1A1
SCHEMBL11295804 0.86 HTR7 (0.37) HTR7ALOX15MEN1KMT2AALDH1A1
SCHEMBL11288531 0.86 HTR7 (0.37) HTR7ALOX15MEN1KMT2AALDH1A1
SCHEMBL11293727 0.85 HTR7 (0.36) HTR7ALOX15MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10499640-B2 Herbicidal compounds SYNGENTA PARTICIPATIONS AG (CH) 2019-12-10 US disclosed
US-20170318810-A1 Herbicidal Compounds SYNGENTA PARTICIPATIONS AG (CH) 2017-11-09 US disclosed
US-20170318810-A1 Herbicidal Compounds SYNGENTA PARTICIPATIONS AG (CH) 2017-11-09 US disclosed
WO-2016071361-A2 HERBICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2016-05-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10499640-B2 Herbicidal compounds DDT, HPD, CBR3 HTR7 3910/4885ALOX15 2750/4885MEN1 4115/4885
US-20170318810-A1 Herbicidal Compounds DDT, HPD, CBR3 HTR7 3910/4885ALOX15 2750/4885MEN1 4115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.