Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | PTPRC | P08575 | 3/20 | 0.41 |
| ▸ | S100A4 | P26447 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10341449 | 0.81 | MAPT (0.43) | ALDH1A1PTPRCS100A4MAPTTDP1 | |
| SCHEMBL11010158 | 0.80 | ALDH1A1 (0.50) | ALDH1A1PTPRCS100A4TDP1BCHE | |
| SCHEMBL14026069 | 0.76 | ALDH1A1 (0.65) | ALDH1A1PTPRCS100A4BCHEACHE | |
| SCHEMBL6673213 | 0.74 | ALDH1A1 (0.51) | ALDH1A1PTPRCS100A4MAPTTDP1 | |
| SCHEMBL4702204 | 0.74 | ALDH1A1 (0.51) | ALDH1A1PTPRCS100A4MAPTTDP1 | |
| SCHEMBL2532509 | 0.74 | ALDH1A1 (0.51) | ALDH1A1PTPRCS100A4MAPTTDP1 | |
| SCHEMBL30095404 | 0.74 | ALDH1A1 (0.51) | ALDH1A1PTPRCS100A4MAPTTDP1 | |
| SCHEMBL15256960 | 0.70 | ALDH1A1 (0.44) | ALDH1A1PTPRCS100A4MAPTBCHE | |
| SCHEMBL29122847 | 0.69 | ALDH1A1 (0.46) | ALDH1A1PTPRCS100A4MAPTTDP1 | |
| SCHEMBL10689729 | 0.69 | ALDH1A1 (0.43) | ALDH1A1CYP19A1CYP3A4CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9638690-B2 | Compounds and compositions for use as alkylating agent sensors and methods of use thereof | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2017-05-02 | — | — | US | disclosed |
| US-9638690-B2 | Compounds and compositions for use as alkylating agent sensors and methods of use thereof | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2017-05-02 | — | — | US | disclosed |
| US-20160131641-A1 | COMPOUNDS AND COMPOSITIONS FOR USE AS ALKYLATING AGENT SENSORS AND METHODS OF USE THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2016-05-12 | — | — | US | disclosed |
| US-20160131641-A1 | COMPOUNDS AND COMPOSITIONS FOR USE AS ALKYLATING AGENT SENSORS AND METHODS OF USE THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2016-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160131641-A1 | COMPOUNDS AND COMPOSITIONS FOR USE AS ALKYLATING AGENT SENSORS AND METHODS OF USE THEREOF | MGMT, MCL1, OGG1 | ALDH1A1 2534/4885PTPRC 2076/4885S100A4 1030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.