Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12586167 | 0.83 | PTPN1 (0.45) | ALDH1A1PTPN1ESR1THRATHRB | |
| SCHEMBL17879957 | 0.83 | LTA4H (0.41) | MAPTHPGDALDH1A1RAB9ANPC1 | |
| SCHEMBL17879995 | 0.83 | LTA4H (0.41) | MAPTHPGDALDH1A1RAB9ANPC1 | |
| SCHEMBL17879953 | 0.81 | ESR1 (0.42) | MAPTHPGDALDH1A1RAB9ANPC1 | |
| SCHEMBL30436898 | 0.81 | ESR1 (0.42) | MAPTHPGDALDH1A1RAB9ANPC1 | |
| SCHEMBL25620251 | 0.80 | PTPN1 (0.46) | MAPTALDH1A1PTPN1TUBB4ATUBB | |
| SCHEMBL14802294 | 0.80 | ESR1 (0.47) | MAPTHPGDALDH1A1RAB9ANPC1 | |
| SCHEMBL47863 | 0.79 | KMT2A (0.49) | MAPTHPGDALDH1A1RAB9ANPC1 | |
| SCHEMBL30399915 | 0.78 | LTA4H (0.56) | MAPTHPGDALDH1A1RAB9ANPC1 | |
| SCHEMBL25986532 | 0.78 | LTA4H (0.56) | MAPTHPGDALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160130406-A1 | STRUCTURE OF PHOSPHOROUS-CONTAINING FUNCTIONALIZED POLY(ARYLENE ETHER) AND COMPOSITIONS PREPARED THEREFROM | Jiangsu Yoke Technology Co., Ltd (CN) | 2016-05-12 | — | — | US | disclosed |