Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 1/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 3/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17738963 | 0.83 | GRN (0.34) | GRNSORT1 | |
| SCHEMBL17738987 | 0.74 | IDO1 (0.39) | — | |
| SCHEMBL17738705 | 0.73 | MC4R (0.32) | — | |
| SCHEMBL17738274 | 0.73 | EPHX1 (0.32) | — | |
| SCHEMBL17738265 | 0.72 | — | — | |
| SCHEMBL17738363 | 0.70 | TDO2 (0.37) | — | |
| SCHEMBL17738962 | 0.68 | NPC1 (0.49) | — | |
| SCHEMBL21894582 | 0.67 | IDO1 (0.44) | METAP2 | |
| SCHEMBL17738304 | 0.64 | SLC6A4 (0.35) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17738258 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016071293-A2 | PHARMACEUTICAL COMPOUND | IOMET PHARMA LTD (GB) | 2016-05-12 | — | — | WO | disclosed |