Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 7/20 | 0.44 |
| ▸ | TDO2 | P48775 | 6/20 | 0.44 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17738413 | 0.85 | IDO1 (0.46) | IDO1TDO2METTL3METAP2 | |
| SCHEMBL30604481 | 0.76 | IDO1 (0.47) | IDO1TDO2METAP2 | |
| SCHEMBL17738420 | 0.76 | IDO1 (0.47) | IDO1TDO2METAP2 | |
| SCHEMBL17738411 | 0.73 | IDO1 (0.43) | IDO1TDO2METAP2CDK2 | |
| SCHEMBL17738576 | 0.70 | JAK2 (0.51) | IDO1TDO2METTL3METAP2 | |
| SCHEMBL16675976 | 0.69 | METAP2 (0.49) | IDO1TDO2METAP2 | |
| SCHEMBL17738290 | 0.68 | METTL3 (0.66) | IDO1TDO2METTL3 | |
| SCHEMBL20042245 | 0.68 | TDO2 (0.46) | IDO1TDO2METAP2 | |
| SCHEMBL17738255 | 0.67 | GRN (0.34) | METAP2 | |
| SCHEMBL17739557 | 0.66 | METAP2 (0.46) | IDO1TDO2METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10590086-B2 | Pharmaceutical compound | IOMET PHARMA LTD. (GB) | 2020-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10590086-B2 | Pharmaceutical compound | IDO1, TDO2, IDO2 | IDO1 1/4885TDO2 2/4885METTL3 1227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.