Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177394 | 0.90 | S1PR1 (0.61) | S1PR1MAPTTAS2R14NPSR1ABCB1 | |
| SCHEMBL177392 | 0.82 | S1PR1 (0.57) | S1PR1MAPTTAS2R14NPSR1KMT2A | |
| SCHEMBL177470 | 0.80 | HSD17B1 (0.42) | S1PR1MAPTMEN1KMT2AABCB1 | |
| SCHEMBL177154 | 0.77 | S1PR5 (0.49) | S1PR1TAS2R14ABCB1 | |
| SCHEMBL178252 | 0.75 | S1PR1 (0.79) | S1PR1MLNR | |
| SCHEMBL177204 | 0.71 | S1PR1 (1.00) | S1PR1MLNRHTT | |
| SCHEMBL177596 | 0.70 | S1PR1 (0.53) | S1PR1MAPTNPSR1MEN1KMT2A | |
| SCHEMBL15512145 | 0.67 | HSD17B1 (0.41) | MAPTTAS2R14MEN1KMT2AHTT | |
| SCHEMBL177322 | 0.65 | S1PR1 (0.59) | S1PR1MAPTMEN1KMT2A | |
| SCHEMBL177580 | 0.62 | S1PR1 (0.42) | S1PR1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344484-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | Akaal Pharma Pty Ltd (AU) | 2011-07-20 | — | — | EP | claimed |
| WO-2010043000-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | AKAAL PHARMA PTY LTD (AU) | 2010-04-22 | — | — | WO | claimed |