SCHEMBL17739935

SCHEMBL17739935

COCCOCCC[SiH](C)C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10570666 1.00 CA2 (0.32) CA2CYP3A4TSHR
SCHEMBL9911589 0.89 MEN1 (0.33) CYP3A4TSHR
SCHEMBL9122599 0.87 TSHR (0.33) TSHR
SCHEMBL19267905 0.84
Triethylene Glycol SCHEMBL10570660 0.82 MEN1 (0.46) TSHR
Fluoride SCHEMBL27919975 0.81
SCHEMBL19503984 0.81 MEN1 (0.31) CA2CYP3A4TSHR
SCHEMBL10570622 0.80 ALDH1A1 (0.36) CYP3A4TSHR
SCHEMBL17803910 0.78 CA2 (0.31) CA2CYP3A4TSHR
SCHEMBL16598028 0.78 MEN1 (0.42) CA2CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110914281-A Siloxane compound and process for producing the same 信越化学工业株式会社 2020-03-24 CN disclosed
US-20160130403-A1 SILICONE CO-POLYMERS AND METHODS OF USE THEREOF TO MODIFY THE SURFACE OF SILICONE ELASTOMERS BY PHYSICAL ADSORPTION McMaster Unviersity (CA) 2016-05-12 US disclosed