Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | NPC1 | O15118 | 7/20 | 0.55 |
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | MAOA | P21397 | 6/20 | 0.53 |
| ▸ | MAOB | P27338 | 6/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | BCL2 | P10415 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809995 | 0.87 | NPC1 (0.57) | XDHMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL16400664 | 0.83 | STS (0.58) | XDHMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL17718192 | 0.83 | ALDH2 (0.74) | MAOAMAOBALDH2 | |
| SCHEMBL17718178 | 0.81 | ALDH2 (0.56) | XDHMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL17722464 | 0.80 | ALDH2 (0.59) | MAPTALDH1A1MAOAMAOBALDH2 | |
| SCHEMBL11937234 | 0.80 | NPC1 (0.52) | XDHMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL16400554 | 0.80 | KDM4E (0.76) | XDHMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL11937233 | 0.79 | ALDH1A1 (0.63) | XDHMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL29089301 | 0.79 | TERT (0.69) | XDHMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL30605366 | 0.79 | TERT (0.69) | XDHMAPTNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016073947-A1 | ANTI-VIRAL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | Kineta, Inc. (US) | 2016-05-12 | — | — | WO | disclosed |