Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25912898 | 0.78 | — | — | |
| SCHEMBL20021192 | 0.78 | CA12 (0.42) | ALDH1A1TSHR | |
| SCHEMBL16019089 | 0.72 | DNM1 (0.38) | EPHX2ALDH1A1TSHRDNM1 | |
| SCHEMBL21863278 | 0.71 | EPHX2 (0.31) | EPHX2 | |
| SCHEMBL16019091 | 0.70 | — | — | |
| SCHEMBL20133635 | 0.70 | — | — | |
| SCHEMBL23823928 | 0.69 | — | — | |
| SCHEMBL20009327 | 0.68 | CA12 (0.34) | TSHR | |
| SCHEMBL10102805 | 0.68 | EPHX2 (0.32) | EPHX2 | |
| SCHEMBL20432161 | 0.67 | DNM1 (0.33) | EPHX2ALDH1A1TSHRDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016073891-A1 | SUBSTITUTED PYRROLO[1,2-A]PYRIMIDINES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | LYSOSOMAL THERAPEUTICS INC. (US) | 2016-05-12 | — | — | WO | disclosed |