Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.48 |
| ▸ | HTR2C | P28335 | 4/20 | 0.45 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 4/20 | 0.36 |
| ▸ | HTR3A | P46098 | 3/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1775407 | 0.99 | HTR6 (0.47) | HTR6HTR2CNMT1ALDH1A1HTR1A | |
| SCHEMBL1777663 | 0.92 | HTR6 (0.48) | HTR6HTR2CALDH1A1HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL1775235 | 0.91 | HTR6 (0.47) | HTR6HTR2CALDH1A1HTR1AHTR3A | |
| SCHEMBL1776290 | 0.88 | HTR6 (0.52) | HTR6HTR2CHTR1AHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL1774443 | 0.87 | HTR6 (0.51) | HTR6HTR2CHTR1AHTR1DHTR1B | |
| SCHEMBL1776434 | 0.81 | HTR2C (0.44) | HTR6HTR2CHTR1AHTR1DHTR1B | |
| SCHEMBL1775158 | 0.81 | HTR2C (0.44) | HTR6HTR2CHTR1AHTR1DHTR1B | |
| SCHEMBL1774912 | 0.81 | HTR6 (0.43) | HTR6HTR2C | |
| Hydrochloric Acid SCHEMBL1776291 | 0.80 | HTR6 (0.43) | HTR6HTR2CHTR1AHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL1775915 | 0.80 | HTR6 (0.43) | HTR6HTR2CHTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943639-B2 | Such as 6-benzenesulfonyl-4-piperazin-1-yl-quinoline hydrochloride; for treatment of central nervous system and/or 5- HT6 receptor related disorders; for weight gain/loss | PROXIMAGEN LIMITED (GB) | 2011-05-17 | — | — | US | claimed |