Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17744145 | 1.00 | ALDH1A1 (0.46) | ALDH1A1CNR1CNR2TRPV1 | |
| SCHEMBL29174557 | 0.90 | ALDH1A1 (0.51) | ALDH1A1CNR1CNR2TRPV1 | |
| SCHEMBL3452404 | 0.90 | ALDH1A1 (0.51) | ALDH1A1CNR1CNR2TRPV1 | |
| SCHEMBL29174551 | 0.88 | ALDH1A1 (0.53) | ALDH1A1CNR1CNR2TRPV1 | |
| SCHEMBL237980 | 0.88 | ALDH1A1 (0.56) | ALDH1A1CNR1CNR2TRPV1 | |
| SCHEMBL13609157 | 0.86 | HTT (0.54) | ALDH1A1 | |
| SCHEMBL8997657 | 0.86 | HTT (0.54) | ALDH1A1 | |
| SCHEMBL30960411 | 0.86 | HTT (0.54) | ALDH1A1 | |
| SCHEMBL686629 | 0.86 | HTT (0.54) | ALDH1A1 | |
| SCHEMBL3937310 | 0.86 | HTT (0.54) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10731159-B2 | Cationic lipid | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2020-08-04 | — | — | US | disclosed |
| US-20200080086-A1 | CATIONIC LIPID | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2020-03-12 | — | — | US | disclosed |
| EP-3020701-B1 | NOVEL LIPID | DAIICHI SANKYO CO LTD (JP) | 2018-09-26 | — | — | EP | disclosed |
| US-20180051285-A1 | CATIONIC LIPID | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2018-02-22 | — | — | US | disclosed |
| US-9803199-B2 | Cationic lipid | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-10-31 | — | — | US | disclosed |
| US-20160257951-A1 | NOVEL LIPID | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-09-08 | — | — | US | disclosed |
| EP-3020701-A1 | NOVEL LIPID | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-05-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160257951-A1 | NOVEL LIPID | NPC1L1, CETP, LIPC | ALDH1A1 1863/4885CNR1 2859/4885CNR2 3109/4885 |
| US-20180051285-A1 | CATIONIC LIPID | CETP, NPC1L1, LIPA | ALDH1A1 2540/4885CNR1 3207/4885CNR2 3384/4885 |
| US-20200080086-A1 | CATIONIC LIPID | CETP, NPC1L1, LIPA | ALDH1A1 2540/4885CNR1 3207/4885CNR2 3384/4885 |
| US-10731159-B2 | Cationic lipid | CETP, NPC1L1, LIPA | ALDH1A1 2540/4885CNR1 3207/4885CNR2 3384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.