SCHEMBL17744812

SCHEMBL17744812

O=C(c1cccc(N(CC2CO2)CC2CO2)c1)c1cccc(N(CC2CO2)CC2CO2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
ALDH1A1 P00352 4/20 0.40
KDM4E B2RXH2 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
POLB P06746 2/20 0.40
HSD17B10 Q99714 2/20 0.40
TP53 P04637 2/20 0.40
TSHR P16473 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
ATM Q13315 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
PTPN1 P18031 2/20 0.37
PARP1 P09874 1/20 0.36
HPGD P15428 2/20 0.35
MAPT P10636 1/20 0.35
PBRM1 Q86U86 1/20 0.34
GAA P10253 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
GFER P55789 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21266627 0.98 L3MBTL1 (0.42) LMNAALDH1A1KDM4ESMN1; SMN2POLB
SCHEMBL21266626 0.97 L3MBTL1 (0.41) LMNAALDH1A1KDM4ESMN1; SMN2POLB
SCHEMBL8762476 0.89 LMNA (0.42) LMNAALDH1A1KDM4ESMN1; SMN2POLB
SCHEMBL19827998 0.88 ATM (0.44) LMNAALDH1A1POLBL3MBTL1ATM
SCHEMBL24037783 0.84 KDM4E (0.32) LMNAALDH1A1KDM4ESMN1; SMN2POLB
SCHEMBL156988 0.83 LMNA (0.45) LMNAALDH1A1KDM4ESMN1; SMN2POLB
SCHEMBL17480430 0.83 LMNA (0.45) LMNAALDH1A1KDM4ESMN1; SMN2POLB
SCHEMBL17744772 0.82 HCRTR1 (0.47) ALDH1A1KDM4ESMN1; SMN2POLBHSD17B10
SCHEMBL30793012 0.81 SRD5A2 (0.42) POLBNPC1RAB9A
SCHEMBL21266625 0.80 HPGD (0.42) LMNAALDH1A1SMN1; SMN2POLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10400076-B2 Epoxy resin composition, prepreg, and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2019-09-03 US disclosed
EP-3020763-B1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2018-08-29 EP disclosed
US-20160152785-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2016-06-02 US disclosed
EP-3020763-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL Toray Industries, Inc. (JP) 2016-05-18 EP disclosed