SCHEMBL17744830

SCHEMBL17744830

Nc1ccc(C(=O)Nc2ccccc2NC(=O)c2cccc(N)c2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.68
NPSR1 Q6W5P4 1/20 0.68
HSD17B10 Q99714 1/20 0.68
MEN1 O00255 7/20 0.60
KMT2A Q03164 7/20 0.60
MAPT P10636 2/20 0.60
CYP1A2 P05177 1/20 0.59
CYP2C9 P11712 1/20 0.59
CYP2C19 P33261 1/20 0.59
HDAC1 Q13547 5/20 0.58
HDAC3 O15379 2/20 0.56
HDAC2 Q92769 2/20 0.56
MAPK1 P28482 1/20 0.56
PTGS1 P23219 1/20 0.55
TERT O14746 1/20 0.54
TOP1 P11387 1/20 0.54
KDM4C Q9H3R0 1/20 0.54
KDM4E B2RXH2 1/20 0.54
ALDH1A1 P00352 1/20 0.54
RAB9A P51151 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17744840 0.93 SMN1; SMN2 (0.71) SMN1; SMN2NPSR1HSD17B10MEN1KMT2A
SCHEMBL17744864 0.88 MEN1 (0.66) SMN1; SMN2MEN1KMT2AMAPTCYP1A2
SCHEMBL5224891 0.87 RAB9A (0.59) SMN1; SMN2NPSR1HSD17B10MEN1KMT2A
SCHEMBL5221783 0.86 F10 (0.73) SMN1; SMN2NPSR1HSD17B10MEN1KMT2A
SCHEMBL17744815 0.85 KMT2A (0.73) SMN1; SMN2NPSR1HSD17B10MEN1KMT2A
SCHEMBL8522632 0.85 HDAC1 (0.72) SMN1; SMN2NPSR1HSD17B10MEN1KMT2A
SCHEMBL17744817 0.84 PTGS1 (0.64) SMN1; SMN2NPSR1HSD17B10MEN1KMT2A
SCHEMBL17744807 0.83 RAB9A (0.58) SMN1; SMN2NPSR1HSD17B10MEN1KMT2A
SCHEMBL21870336 0.83 POLB (0.68) SMN1; SMN2NPSR1HSD17B10MEN1KMT2A
SCHEMBL3769385 0.83 NPSR1 (0.80) SMN1; SMN2NPSR1HSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10400076-B2 Epoxy resin composition, prepreg, and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2019-09-03 US disclosed
CN-105392838-B Composition epoxy resin, prepreg and carbon fibre reinforced composite 东丽株式会社 2018-12-14 CN disclosed
EP-3020763-B1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2018-08-29 EP disclosed
US-20160152785-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2016-06-02 US disclosed
EP-3020763-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL Toray Industries, Inc. (JP) 2016-05-18 EP disclosed