SCHEMBL17744864

SCHEMBL17744864

Nc1ccc(C(=O)Nc2ccccc2NC(=O)c2ccc(N)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.66
KMT2A Q03164 4/20 0.66
POLB P06746 2/20 0.64
LMNA P02545 1/20 0.64
PKM P14618 1/20 0.64
APEX1 P27695 1/20 0.64
TDP1 Q9NUW8 1/20 0.64
HDAC1 Q13547 5/20 0.63
HDAC3 O15379 3/20 0.63
HDAC2 Q92769 3/20 0.63
MAPK1 P28482 1/20 0.63
NCOR2 Q9Y618 1/20 0.61
GAA P10253 1/20 0.60
F10 P00742 1/20 0.59
PTGS1 P23219 1/20 0.57
CYP1A2 P05177 1/20 0.57
MAPT P10636 1/20 0.57
CYP2C9 P11712 1/20 0.57
CYP2C19 P33261 1/20 0.57
TOP1 P11387 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1705539 0.93 HDAC1 (0.61) MEN1KMT2APOLBLMNAPKM
SCHEMBL10373756 0.91 GAA (0.57) MEN1KMT2APOLBLMNAPKM
Dinaline SCHEMBL29354254 0.90 HDAC1 (0.79) HDAC1HDAC3HDAC2MAPK1NCOR2
Dinaline SCHEMBL93636 0.90 HDAC1 (0.79) HDAC1HDAC3HDAC2MAPK1NCOR2
Dinaline SCHEMBL10373837 0.89 HDAC1 (0.77) HDAC1HDAC3HDAC2MAPK1NCOR2
SCHEMBL17744793 0.88 HDAC1 (0.60) MEN1KMT2APOLBLMNAPKM
SCHEMBL5224950 0.88 RAB9A (0.68) MEN1KMT2APOLBHDAC1MAPK1
SCHEMBL17744830 0.88 SMN1; SMN2 (0.68) MEN1KMT2APOLBLMNAPKM
SCHEMBL683706 0.87 POLB (0.74) MEN1KMT2APOLBLMNAPKM
SCHEMBL29466160 0.87 RAB9A (0.71) MEN1KMT2APOLBLMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10400076-B2 Epoxy resin composition, prepreg, and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2019-09-03 US disclosed
CN-105392838-B Composition epoxy resin, prepreg and carbon fibre reinforced composite 东丽株式会社 2018-12-14 CN disclosed
EP-3020763-B1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2018-08-29 EP disclosed
US-20160152785-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2016-06-02 US disclosed
EP-3020763-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL Toray Industries, Inc. (JP) 2016-05-18 EP disclosed