SCHEMBL17744844

SCHEMBL17744844

Nc1cccc(C(=O)Oc2ccc(OC(=O)c3ccccc3N)cc2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.55
HSD17B10 Q99714 6/20 0.55
KDM4E B2RXH2 3/20 0.55
HPGD P15428 3/20 0.55
GLA P06280 1/20 0.55
MAPT P10636 6/20 0.49
HDAC6 Q9UBN7 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
LMNA P02545 1/20 0.49
TP53 P04637 1/20 0.49
CYP3A4 P08684 1/20 0.49
ADORA3 P0DMS8 1/20 0.49
CHRM1 P11229 1/20 0.49
TBXA2R P21731 1/20 0.49
SLC6A2 P23975 1/20 0.49
PDE4A P27815 1/20 0.49
ADRA1A P35348 1/20 0.49
KDR P35968 1/20 0.49
SLC6A3 Q01959 1/20 0.49
PARP10 Q53GL7 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17744789 0.93 MAPT (0.48) ALDH1A1HSD17B10KDM4EHPGDGLA
SCHEMBL17744839 0.88 ALDH1A1 (0.46) ALDH1A1HSD17B10KDM4EHPGDGLA
SCHEMBL26103700 0.87 PBRM1 (0.53) ALDH1A1HSD17B10KDM4EMAPTHDAC6
SCHEMBL29930784 0.87 PBRM1 (0.53) ALDH1A1HSD17B10KDM4EMAPTHDAC6
SCHEMBL17744895 0.84 SMN1; SMN2 (0.54) ALDH1A1HSD17B10KDM4EHPGDGLA
SCHEMBL707848 0.84 KMT2A (0.51) ALDH1A1HSD17B10KDM4EMAPTHDAC6
SCHEMBL29846109 0.84 KMT2A (0.51) ALDH1A1HSD17B10KDM4EMAPTHDAC6
SCHEMBL8613426 0.84 PBRM1 (0.59) ALDH1A1MAPTHDAC6SMN1; SMN2LMNA
SCHEMBL9861291 0.84 HSD17B10 (0.71) ALDH1A1HSD17B10KDM4EHPGDGLA
SCHEMBL17744854 0.83 ALDH1A1 (0.58) ALDH1A1HSD17B10KDM4EHPGDGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10400076-B2 Epoxy resin composition, prepreg, and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2019-09-03 US disclosed
EP-3020763-B1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2018-08-29 EP disclosed
US-20160152785-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2016-06-02 US disclosed
EP-3020763-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL Toray Industries, Inc. (JP) 2016-05-18 EP disclosed