SCHEMBL17744895

SCHEMBL17744895

Nc1cccc(OC(=O)c2ccccc2N)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.54
MAPT P10636 3/20 0.54
CYP3A4 P08684 3/20 0.54
TP53 P04637 2/20 0.54
LMNA P02545 1/20 0.54
ADORA3 P0DMS8 1/20 0.54
CHRM1 P11229 1/20 0.54
TBXA2R P21731 1/20 0.54
SLC6A2 P23975 1/20 0.54
PDE4A P27815 1/20 0.54
ADRA1A P35348 1/20 0.54
KDR P35968 1/20 0.54
SLC6A3 Q01959 1/20 0.54
HDAC6 Q9UBN7 1/20 0.54
ALDH1A1 P00352 12/20 0.52
HSD17B10 Q99714 10/20 0.52
KDM4E B2RXH2 6/20 0.52
HPGD P15428 5/20 0.52
GLA P06280 2/20 0.52
CFTR P13569 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28261883 0.91 MAPT (0.58) SMN1; SMN2MAPTCYP3A4TP53LMNA
SCHEMBL9861954 0.91 ALDH1A1 (0.56) SMN1; SMN2MAPTCYP3A4TP53LMNA
SCHEMBL17744789 0.90 MAPT (0.48) SMN1; SMN2MAPTCYP3A4TP53LMNA
SCHEMBL28261900 0.88 MAPT (0.49) SMN1; SMN2MAPTCYP3A4TP53LMNA
SCHEMBL28150196 0.85 MAPT (0.56) SMN1; SMN2MAPTCYP3A4TP53LMNA
SCHEMBL28261885 0.85 MAPT (0.60) SMN1; SMN2MAPTCYP3A4TP53LMNA
SCHEMBL17744844 0.84 ALDH1A1 (0.55) SMN1; SMN2MAPTCYP3A4TP53LMNA
SCHEMBL17744876 0.84 MAPT (0.49) SMN1; SMN2MAPTCYP3A4TP53LMNA
SCHEMBL444509 0.84 HSD17B10 (0.64) SMN1; SMN2MAPTCYP3A4TP53LMNA
SCHEMBL9861871 0.84 HSD17B10 (0.60) SMN1; SMN2MAPTCYP3A4TP53LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10400076-B2 Epoxy resin composition, prepreg, and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2019-09-03 US disclosed
CN-105392838-B Composition epoxy resin, prepreg and carbon fibre reinforced composite 东丽株式会社 2018-12-14 CN disclosed
EP-3020763-B1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2018-08-29 EP disclosed
US-20160152785-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2016-06-02 US disclosed
EP-3020763-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL Toray Industries, Inc. (JP) 2016-05-18 EP disclosed
CN-105392838-A Epoxy resin composition, prepreg, and carbon fiber-reinforced composite material TORAY INDUSTRIES 2016-03-09 CN disclosed