SCHEMBL1774697

SCHEMBL1774697

O=[N+]([O-])C(Br)(Br)C(Br)(Br)[N+](=O)[O-]

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
TSHR P16473 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
LMNA P02545 1/20 0.45
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HPGD P15428 1/20 0.35
HIF1A Q16665 1/20 0.35
CA5A P35218 1/20 0.33
CA5B Q9Y2D0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1775867 0.78
SCHEMBL27800501 0.75
SCHEMBL1603248 0.75
SCHEMBL9452610 0.75 ALDH1A1 (0.47) ALDH1A1TSHRTDP1LMNAMEN1
SCHEMBL9778209 0.72
SCHEMBL29060558 0.72
SCHEMBL899692 0.72
SCHEMBL1720725 0.72
SCHEMBL8060213 0.72
SCHEMBL28013679 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1917231-B1 PROCESS OF PREPARING BROMOPICRIN BROMINE COMPOUNDS LTD (IL) 2013-10-02 EP disclosed
US-8415513-B2 Continuous process of preparing bromopicrin BROMINE COMPOUNDS LTD. (IL) 2013-04-09 US disclosed
US-7943806-B2 Process of preparing bromopicrin BROMINE COMPOUNDS LTD. (IL) 2011-05-17 US disclosed
US-20100204528-A1 CONTINUOUS PROCESS OF PREPARING BROMOPICRIN BROMINE COMPOUNDS LTD. (IL) 2010-08-12 US disclosed
US-20100152501-A1 Process of preparing bromopicrin BROMINE COMPOUNDS LTD. (IL) 2010-06-17 US disclosed
EP-1917231-A4 PROCESS OF PREPARING BROMOPICRIN BROMINE COMPOUNDS LTD (IL) 2008-11-12 EP disclosed
EP-1917231-A2 PROCESS OF PREPARING BROMOPICRIN Bromine Compounds Ltd. (IL) 2008-05-07 EP disclosed
WO-2007023496-A2 PROCESS OF PREPARING BROMOPICRIN BROMINE COMPOUNDS LTD. (IL) 2007-03-01 WO disclosed
EP-0341496-B1 Modified diene polymer rubbers SUMITOMO CHEMICAL CO (JP) 1993-10-20 EP disclosed
US-5219938-A Reacting a living polymer of a conjugated diene with a tin or silicon compound and with a nitro compound, a phosphoryl chloride, aminosilane, an acrylamide or an aminovinylsilane; auto tires; impact strength; cold resistance; storage SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-15 US disclosed
US-5128416-A Automobile tire treads SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-07-07 US disclosed
US-5015692-A Rubbers for tires having impact strength SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-05-14 US disclosed
US-4957976-A IMPROVED PROPERTIES FOR AUTOMOBILE TIRES, MODIFIED WITH PHOSPHORYL CHLORIDE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1990-09-18 US disclosed
EP-0341496-A2 Modified diene polymer rubbers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-11-15 EP disclosed
EP-0270071-A2 Process for preparing modified diene polymer rubbers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-06-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100152501-A1 Process of preparing bromopicrin NEFM, BRPF1, NPM1 ALDH1A1 4017/4885TSHR 3112/4885TDP1 1248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.