Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 11/20 | 0.89 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.89 |
| ▸ | PDE4A | P27815 | 11/20 | 0.89 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.89 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.89 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.89 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.89 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4423680 | 0.94 | ADORA2B (1.00) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| 1-Methylxanthine SCHEMBL10996 | 0.87 | ADORA2B (1.00) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL27395394 | 0.86 | ADORA2B (1.00) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL6233166 | 0.86 | ADORA2B (1.00) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| 1-Methylxanthine SCHEMBL27529726 | 0.85 | ADORA2B (0.96) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| 1-Methylxanthine SCHEMBL9682658 | 0.85 | ADORA2B (0.96) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| 1-Methylxanthine SCHEMBL28309011 | 0.85 | ADORA2B (0.96) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL1892011 | 0.84 | ADORA2B (0.92) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL21381249 | 0.83 | ADORA2B (0.89) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL11661797 | 0.83 | ADORA2B (0.89) | ADORA2BADORA2APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3217985-A1 | COMPOUNDS FOR THE TREATMENT OF MYOTONIC DYSTROPHY | Universitat de València (ES) | 2017-09-20 | — | — | EP | disclosed |
| WO-2016075285-A1 | COMPOUNDS FOR THE TREATMENT OF MYOTONIC DYSTROPHY | UNIVERSITAT DE VALÈNCIA (ES) | 2016-05-19 | — | — | WO | disclosed |