Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 9/20 | 0.47 |
| ▸ | CALML3 | P27482 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SDHA | P31040 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17749416 | 1.00 | MAOA (0.47) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1034329 | 0.93 | MAOA (0.44) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1034816 | 0.93 | MAOA (0.44) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL4649597 | 0.88 | MAOA (0.47) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1033802 | 0.87 | MAOA (0.48) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1033798 | 0.87 | MAOA (0.48) | MAOACALML3MAOBLMNAPTGS1 | |
| Hydrochloric Acid SCHEMBL1033523 | 0.86 | MAOA (0.48) | MAOACALML3MAOBLMNAPTGS1 | |
| Hydrochloric Acid SCHEMBL1033525 | 0.86 | MAOA (0.48) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL10197586 | 0.82 | MAOA (0.48) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1031534 | 0.81 | MAOA (0.44) | MAOACALML3MAOBLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3217974-A1 | METHOD FOR TREATING, PREVENTING, OR REDUCING THE RISK OF SKIN INFECTION | Melinta Therapeutics, Inc. (US) | 2017-09-20 | — | — | EP | disclosed |
| WO-2016077818-A1 | METHOD FOR TREATING, PREVENTING, OR REDUCING THE RISK OF SKIN INFECTION | MELINTA THERAPEUTICS, INC. (US) | 2016-05-19 | — | — | WO | disclosed |