Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 1.00 |
| ▸ | TP53 | P04637 | 8/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | F8 | P00451 | 1/20 | 1.00 |
| ▸ | F5 | P12259 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 7/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | IDE | P14735 | 1/20 | 0.68 |
| ▸ | XBP1 | P17861 | 1/20 | 0.68 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2568428 | 0.86 | SMN1; SMN2 (0.84) | SMN1; SMN2TP53MAPTF8F5 | |
| SCHEMBL7629030 | 0.85 | SMN1; SMN2 (0.82) | SMN1; SMN2TP53MAPTF8F5 | |
| SCHEMBL17749503 | 0.85 | SMN1; SMN2 (0.74) | SMN1; SMN2TP53MAPTF8F5 | |
| SCHEMBL17749595 | 0.83 | SMN1; SMN2 (0.70) | SMN1; SMN2TP53MAPTF8F5 | |
| SCHEMBL2505043 | 0.82 | LMNA (0.98) | SMN1; SMN2TP53MAPTF8F5 | |
| SCHEMBL17761713 | 0.81 | TP53 (0.71) | SMN1; SMN2TP53MAPTF8F5 | |
| SCHEMBL17749565 | 0.81 | TP53 (0.71) | SMN1; SMN2TP53MAPTF8F5 | |
| SCHEMBL17761742 | 0.81 | TP53 (0.71) | SMN1; SMN2TP53MAPTF8F5 | |
| SCHEMBL17749492 | 0.80 | LMNA (0.73) | SMN1; SMN2TP53MAPTF8F5 | |
| SCHEMBL17761945 | 0.80 | SMN1; SMN2 (0.66) | SMN1; SMN2TP53MAPTF8F5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016077541-A1 | NOVEL ANTI-INFECTIVE COMPOUNDS AND METHODS USING SAME | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-05-19 | — | — | WO | claimed |
| WO-2016077541-A1 | NOVEL ANTI-INFECTIVE COMPOUNDS AND METHODS USING SAME | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-05-19 | — | — | WO | disclosed |
| WO-2016077541-A1 | NOVEL ANTI-INFECTIVE COMPOUNDS AND METHODS USING SAME | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-05-19 | — | — | WO | disclosed |