Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSH | P09668 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 3/20 | 0.33 |
| ▸ | MMP7 | P09237 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6568659 | 1.00 | POLB (0.39) | POLBCNR2ALDH1A1KDM4EMEN1 | |
| SCHEMBL16199147 | 1.00 | POLB (0.39) | POLBCNR2ALDH1A1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL19809583 | 0.98 | POLB (0.38) | POLBCNR2ALDH1A1KDM4EMEN1 | |
| SCHEMBL6570732 | 0.94 | CSNK1E (0.39) | POLBCNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL14434711 | 0.94 | CSNK1E (0.39) | POLBCNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL6570834 | 0.92 | CSNK1E (0.41) | CNR2ALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL19009994 | 0.88 | SMN1; SMN2 (0.38) | POLBSMN1; SMN2 | |
| SCHEMBL6569762 | 0.88 | SMN1; SMN2 (0.38) | POLBSMN1; SMN2 | |
| SCHEMBL9308091 | 0.87 | CYP3A4 (0.41) | — | |
| SCHEMBL9309105 | 0.87 | CYP3A4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667638-B2 | 4-substitued cytisine analogues | THE UNIVERSITY OF BRISTOL | 2023-06-06 | — | — | US | disclosed |
| EP-3596038-B1 | METAL-CATALYZED ALKOXYCARBONYLATION OF A LACTONE | QATAR FOUND EDUCATION SCIENCE & COMMUNITY DEV (US) | 2022-12-28 | — | — | EP | disclosed |
| US-20200172544-A1 | COMPOUNDS | THE UNIVERSITY OF BRISTOL (GB) | 2020-06-04 | — | — | US | disclosed |
| WO-2018104176-A1 | AMINE DERIVATIVES OF THE BETA-FARNESENE | CLARIANT INTERNATIONAL LTD (CH) | 2018-06-14 | — | — | WO | disclosed |
| US-9340485-B2 | Process for preparing esters from formates and olefinically unsaturated compounds | EVONIK INDUSTRIES AG (DE) | 2016-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11667638-B2 | 4-substitued cytisine analogues | CES2, CDA, PCYT1A | POLB 699/4885CNR2 26/4885ALDH1A1 1941/4885 |
| US-20200172544-A1 | COMPOUNDS | CES2, CYCS, CHKB | POLB 777/4885CNR2 10/4885ALDH1A1 1652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.