Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12696399 | 1.00 | NQO2 (0.44) | NQO2MTNR1AMTNR1BEPHX2MIF | |
| SCHEMBL20505740 | 0.85 | EPHX2 (0.50) | MTNR1AMTNR1BEPHX2DRD2IDO1 | |
| SCHEMBL29572544 | 0.85 | EPHX2 (0.50) | MTNR1AMTNR1BEPHX2DRD2IDO1 | |
| SCHEMBL14493800 | 0.83 | MTNR1A (0.45) | NQO2MTNR1AMTNR1BNPSR1IDO1 | |
| SCHEMBL13686477 | 0.82 | LATS1 (0.44) | EPHX2MIFNPSR1IDO1EPHX1 | |
| SCHEMBL10175565 | 0.74 | TRPV1 (0.50) | NQO2MTNR1AMTNR1BTRPV1EPHX1 | |
| SCHEMBL14234588 | 0.73 | EGFR (0.35) | — | |
| SCHEMBL1161006 | 0.73 | EPHX2 (0.38) | EPHX2MIFDRD2 | |
| SCHEMBL1311096 | 0.71 | MTNR1A (0.62) | NQO2MTNR1AMTNR1B | |
| SCHEMBL12369307 | 0.70 | CHRNB2 (0.37) | MIFDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2688883-B1 | PYRIMIDINE DERIVATIVES | NOVIGA RES AB (SE) | 2016-05-18 | — | — | EP | disclosed |