SCHEMBL17751192

SCHEMBL17751192

CCO[C@H](CO)CC(F)F

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14315064 0.84 LMNA (0.36) THRBLMNA
SCHEMBL15880022 0.80 THRB (0.36) THRBLMNA
SCHEMBL337832 0.79
SCHEMBL31506492 0.78 LMNA (0.39) THRBLMNA
SCHEMBL29244100 0.78 THRB (0.35) THRBLMNA
SCHEMBL6856831 0.76 LMNA (0.36) THRBLMNA
SCHEMBL14313542 0.76 TDP1 (0.41) THRBLMNA
SCHEMBL13770688 0.74
SCHEMBL225234 0.74
SCHEMBL14314775 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2080779-B1 POLYMERIC DERIVATIVE OF NUCLEIC ACID METABOLIC ANTAGONIST NIPPON KAYAKU KK (JP) 2016-05-18 EP disclosed