SCHEMBL17752159

SCHEMBL17752159

COc1c(C)cc(CO)cc1COCc1cc(C)cc(CO)c1O

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.44
SHBG P04278 1/20 0.44
KDM4E B2RXH2 1/20 0.38
CASP6 P55212 1/20 0.38
PTPN1 P18031 2/20 0.34
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33
DHFR P00374 1/20 0.32
MAOA P21397 1/20 0.31
ACHE P22303 1/20 0.31
AMY1A P0DUB6 1/20 0.30
AKR1B1 P15121 1/20 0.30
GFER P55789 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17702500 0.87 SHBG (0.59) MAPTSHBGKDM4ECASP6MAOA
SCHEMBL14148149 0.82 SHBG (0.47) MAPTSHBGKDM4ECASP6FNTA
SCHEMBL19309299 0.78 SHBG (0.44) MAPTSHBGKDM4ECASP6MAOA
SCHEMBL4111195 0.78 MAPT (0.44) MAPTPTPN1FNTAFNTBACHE
SCHEMBL16240772 0.77 MAPT (0.46) MAPTSHBGKDM4ECASP6FNTA
SCHEMBL16001165 0.76 SHBG (0.42) MAPTSHBGKDM4ECASP6FNTA
SCHEMBL18073402 0.75 PRKCE (0.44) MAPTSHBGKDM4ECASP6ACHE
SCHEMBL20362610 0.75 MAPT (0.47) MAPTSHBGPTPN1FNTAFNTB
SCHEMBL9146572 0.74 TSHR (0.47) MAPTSHBGKDM4E
SCHEMBL15344722 0.73 SHBG (0.55) MAPTSHBGKDM4ECASP6ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9598602-B2 Thermosetting compositions based on phenolic resins and curable poleyester resins made with diketene or beta-ketoacetate containing compounds EASTMAN CHEMICAL COMPANY (US) 2017-03-21 US disclosed
US-20160137877-A1 THERMOSETTING COMPOSITIONS BASED ON PHENOLIC RESINS AND CURABLE POLEYESTER RESINS MADE WITH DIKETENE OR BETA-KETOACETATE CONTAINING COMPOUNDS EASTMAN CHEMICAL COMPANY (US) 2016-05-19 US disclosed