SCHEMBL14148149

SCHEMBL14148149

Cc1cc(CO)c(O)c(COCc2cc(C)cc(CO)c2O)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.47
AMY1A P0DUB6 1/20 0.41
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
HIF1A Q16665 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HSPA5 P11021 1/20 0.37
ALDH1A1 P00352 4/20 0.37
LMNA P02545 2/20 0.37
MAPT P10636 2/20 0.37
HPGD P15428 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
MAOA P21397 1/20 0.36
HSD17B10 Q99714 2/20 0.36
CYP2D6 P10635 1/20 0.36
SELL P14151 1/20 0.36
SELP P16109 1/20 0.36
SELE P16581 1/20 0.36
KDM4E B2RXH2 3/20 0.35
CASP6 P55212 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19309299 0.96 SHBG (0.44) SHBGAMY1ACYP2C9CYP2C19HIF1A
SCHEMBL16001165 0.93 SHBG (0.42) SHBGAMY1ACYP2C9CYP2C19HIF1A
SCHEMBL19308127 0.89 SHBG (0.40) SHBGAMY1ACYP2C9CYP2C19HIF1A
SCHEMBL17702500 0.88 SHBG (0.59) SHBGAMY1ACYP2C9CYP2C19HIF1A
SCHEMBL9146572 0.87 TSHR (0.47) SHBGSMN1; SMN2ALDH1A1LMNAMAPT
SCHEMBL187792 0.87 SHBG (0.52) SHBGAMY1ACYP2C9CYP2C19HIF1A
SCHEMBL13140673 0.86 PRKCE (0.46) SHBGAMY1ACYP2C9CYP2C19HIF1A
SCHEMBL10597874 0.82 TSHR (0.50) SHBGSMN1; SMN2ALDH1A1LMNAMAPT
SCHEMBL17752159 0.82 MAPT (0.44) SHBGAMY1AMAPTMAOAKDM4E
SCHEMBL22222032 0.81 AMY1A (0.49) SHBGAMY1ACYP2C9CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9752010-B2 Phosphorus-containing compounds useful for making halogen-free, ignition-resistant polymers BLUE CUBE IP LLC (US) 2017-09-05 US disclosed
US-9752010-B2 Phosphorus-containing compounds useful for making halogen-free, ignition-resistant polymers BLUE CUBE IP LLC (US) 2017-09-05 US disclosed
US-20160319107-A1 PHOSPHORUS-CONTAINING COMPOUNDS USEFUL FOR MAKING HALOGEN-FREE, IGNITION-RESISTANT POLYMERS DOW GLOBAL TECHNOLOGIES LLC 2016-11-03 US disclosed
US-20160319107-A1 PHOSPHORUS-CONTAINING COMPOUNDS USEFUL FOR MAKING HALOGEN-FREE, IGNITION-RESISTANT POLYMERS DOW GLOBAL TECHNOLOGIES LLC 2016-11-03 US disclosed
US-9388297-B2 Phosphorus-containing compounds useful for making halogen-free, ignition-resistant polymers BLUE CUBE IP LLC (US) 2016-07-12 US disclosed
US-9388297-B2 Phosphorus-containing compounds useful for making halogen-free, ignition-resistant polymers BLUE CUBE IP LLC (US) 2016-07-12 US disclosed
US-20140249253-A1 PHOSPHORUS-CONTAINING COMPOUNDS USEFUL FOR MAKING HALOGEN-FREE, IGNITION-RESISTANT POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2014-09-04 US disclosed
US-20140249253-A1 PHOSPHORUS-CONTAINING COMPOUNDS USEFUL FOR MAKING HALOGEN-FREE, IGNITION-RESISTANT POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2014-09-04 US disclosed
WO-2012161926-A2 PHOSPHORUS-CONTAINING COMPOUNDS USEFUL FOR MAKING HALOGEN-FREE, IGNITION-RESISTANT POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-11-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160319107-A1 PHOSPHORUS-CONTAINING COMPOUNDS USEFUL FOR MAKING HALOGEN-FREE, IGNITION-RESISTANT POLYMERS RBBP4, REL, EWSR1 SHBG 3048/4885AMY1A 3715/4885CYP2C9 2367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.