SCHEMBL17752276

SCHEMBL17752276

O=c1c2ccccc2sc2cc(-c3ccc(N4c5ccccc5C5(c6ccccc6Sc6ccccc65)c5ccccc54)cc3)ccc12

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.34
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HDAC6 Q9UBN7 1/20 0.32
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
PKM P14618 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19175997 0.96 KDM4E (0.32) KDM4ENPC1RAB9AALDH1A1MAPT
SCHEMBL17752277 0.91 KDM4E (0.37) KDM4ENPC1RAB9AALDH1A1MAPT
SCHEMBL17752275 0.90
SCHEMBL17752269 0.89 KDM4E (0.36) KDM4ENPC1RAB9AALDH1A1MAPT
SCHEMBL17752274 0.88 HDAC6 (0.33) KDM4EHDAC6
SCHEMBL19176040 0.87
SCHEMBL17752265 0.87 KDM4E (0.36) KDM4ENPC1RAB9AALDH1A1MAPT
SCHEMBL17752267 0.86 KDM4E (0.34) KDM4ENPC1RAB9AALDH1A1MAPT
SCHEMBL17850976 0.84 KDM4E (0.36) KDM4ENPC1RAB9AALDH1A1MAPT
SCHEMBL19175873 0.82 KDM4E (0.31) KDM4ENPC1RAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3171421-B1 ORGANIC LIGHT-EMITTING ELEMENT UNIV KYUSHU NAT UNIV CORP (JP) 2023-01-25 EP disclosed
US-20210074927-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2021-03-11 US disclosed
US-10862047-B2 Organic electroluminescent device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2020-12-08 US disclosed
EP-3706182-A1 ORGANIC ELECTROLUMINESCENT DEVICE Kyushu University National University Corporation (JP) 2020-09-09 EP disclosed
US-10658596-B2 2020-05-19 US disclosed
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND KYULUX, INC. (JP) 2017-07-27 US disclosed
US-9685615-B2 Light emitting material, delayed fluorescent emitter, organic light emitting device, and compound KYULUX, INC. (JP) 2017-06-20 US disclosed
US-9685615-B2 Light emitting material, delayed fluorescent emitter, organic light emitting device, and compound KYULUX, INC. (JP) 2017-06-20 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
EP-3171421-A1 ORGANIC LIGHT-EMITTING ELEMENT Kyushu University, National University Corporation (JP) 2017-05-24 EP disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed
US-20160141516-A1 LIGHT EMITTING MATERIAL, DELAYED FLUORESCENT EMITTER, ORGANIC LIGHT EMITTING DEVICE, AND COMPOUND KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-05-19 US disclosed
US-20160141516-A1 LIGHT EMITTING MATERIAL, DELAYED FLUORESCENT EMITTER, ORGANIC LIGHT EMITTING DEVICE, AND COMPOUND KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160141516-A1 LIGHT EMITTING MATERIAL, DELAYED FLUORESCENT EMITTER, ORGANIC LIGHT EMITTING DEVICE, AND COMPOUND CRY2, CRY1, IK KDM4E 3808/4885NPC1 3738/4885RAB9A 994/4885
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND CRY1, CRY2, CYBA KDM4E 2784/4885NPC1 3146/4885RAB9A 4082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.