SCHEMBL1775360

SCHEMBL1775360

Cc1ccc(-c2ccccc2C)c(C(=O)O)c1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.53
CSNK2A1 P68400 1/20 0.52
MYC P01106 1/20 0.51
POLB P06746 1/20 0.50
GAA P10253 1/20 0.49
TTR P02766 1/20 0.49
EIF4E P06730 1/20 0.47
FOLH1 Q04609 1/20 0.46
METAP2 P50579 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
NOTUM Q6P988 1/20 0.45
KDM5A P29375 1/20 0.44
KDM4C Q9H3R0 1/20 0.44
KDM5B Q9UGL1 1/20 0.44
ELANE P08246 1/20 0.44
NFE2L2 Q16236 1/20 0.44
DHODH Q02127 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4371510 0.89 GAA (0.59) CSNK2A1MYCPOLBGAATTR
SCHEMBL6702122 0.87 MYC (0.58) CSNK2A1MYCPOLBGAAEIF4E
SCHEMBL18116578 0.87 CSNK2A1 (0.57) CSNK2A1MYCPOLBGAAEIF4E
SCHEMBL4621112 0.87 CSNK2A1 (0.65) MCL1CSNK2A1POLBGAATTR
SCHEMBL29064695 0.86 MYC (0.56) MCL1CSNK2A1MYCPOLBGAA
SCHEMBL4915994 0.84 TTR (0.51) MCL1MYCPOLBTTREIF4E
SCHEMBL14397372 0.84 POLB (0.53) CSNK2A1MYCPOLBGAATTR
SCHEMBL11080302 0.84 EIF4E (0.52) MCL1MYCEIF4EFOLH1
SCHEMBL9534481 0.83 MYC (0.60) MCL1MYCGAATTRFOLH1
SCHEMBL30755384 0.83 MYC (0.71) MCL1MYCPOLBGAAFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7943781-B2 Process for preparing telmisartan DR. REDDY'S LABORATORIES LIMITED (IN) 2011-05-17 US disclosed
EP-1805146-A4 PROCESS FOR PREPARING TELMISARTAN REDDYS LAB LTD DR (IN) 2009-01-14 EP disclosed
US-20070287840-A1 Process for Preparing Telmisartan DR. REDDY'S LABORATORIES LIMITED (IN) 2007-12-13 US disclosed
EP-1805146-A2 PROCESS FOR PREPARING TELMISARTAN Dr. Reddy's Laboratories Ltd. (IN) 2007-07-11 EP disclosed
WO-2006044754-A2 PROCESS FOR PREPARING TELMISARTAN DR. REDDY'S LABORATORIES LTD. (IN) 2006-04-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070287840-A1 Process for Preparing Telmisartan AGT, TTR, REN MCL1 4092/4885CSNK2A1 1812/4885MYC 3253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.