Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CECR2 | Q9BXF3 | 7/20 | 0.54 |
| ▸ | TAF1 | P21675 | 5/20 | 0.54 |
| ▸ | BRD9 | Q9H8M2 | 5/20 | 0.54 |
| ▸ | BRD4 | O60885 | 9/20 | 0.47 |
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17753698 | 0.81 | CECR2 (0.51) | CECR2TAF1BRD9BRD4 | |
| SCHEMBL17754062 | 0.81 | CECR2 (0.51) | CECR2TAF1BRD9BRD4 | |
| SCHEMBL17753686 | 0.80 | BRD4 (0.52) | CECR2TAF1BRD9BRD4 | |
| SCHEMBL17754023 | 0.79 | CECR2 (0.62) | CECR2TAF1BRD9BRD4 | |
| SCHEMBL19639705 | 0.79 | CECR2 (0.54) | CECR2TAF1BRD9BRD4CNR1 | |
| SCHEMBL17748995 | 0.79 | CECR2 (0.54) | CECR2TAF1BRD9BRD4CNR1 | |
| SCHEMBL17754104 | 0.79 | CECR2 (0.54) | CECR2TAF1BRD9BRD4CNR1 | |
| SCHEMBL17753898 | 0.78 | BRD4 (0.53) | CECR2TAF1BRD9BRD4 | |
| SCHEMBL17753771 | 0.78 | CECR2 (0.55) | CECR2TAF1BRD9BRD4 | |
| SCHEMBL17753665 | 0.77 | TAF1 (0.52) | CECR2TAF1BRD9BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170340604-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2017-11-30 | — | — | US | disclosed |
| WO-2016077375-A1 | BROMODOMAIN INHIBITORS AND USES THEREOF | GENENTECH, INC. (US) | 2016-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170340604-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | BRD4, BRDT, BRD3 | CECR2 184/4885TAF1 439/4885BRD9 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.