Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 10/20 | 0.74 |
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1775358 | 0.99 | HTR6 (0.72) | HTR6HTR2CALDH1A1L3MBTL1RAB9A | |
| SCHEMBL1777219 | 0.92 | HTR6 (0.74) | HTR6HTR2CALDH1A1L3MBTL1MEN1 | |
| Hydrochloric Acid SCHEMBL1776090 | 0.91 | HTR6 (0.72) | HTR6HTR2CALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1775698 | 0.86 | HTR6 (0.78) | HTR6HTR2CHTR1ADRD2HTR7 | |
| SCHEMBL1777317 | 0.83 | HTR6 (0.74) | HTR6HTR2CALDH1A1L3MBTL1MEN1 | |
| Hydrochloric Acid SCHEMBL1780248 | 0.82 | HTR6 (0.72) | HTR6HTR2CALDH1A1L3MBTL1MEN1 | |
| SCHEMBL3680498 | 0.82 | HTR6 (0.66) | HTR6HTR2C | |
| SCHEMBL1780383 | 0.81 | HTR6 (0.92) | HTR6HTR2CL3MBTL1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1778263 | 0.80 | HTR6 (0.90) | HTR6HTR2CL3MBTL1MEN1KMT2A | |
| SCHEMBL1776166 | 0.80 | HTR6 (0.66) | HTR6HTR2CHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943639-B2 | Such as 6-benzenesulfonyl-4-piperazin-1-yl-quinoline hydrochloride; for treatment of central nervous system and/or 5- HT6 receptor related disorders; for weight gain/loss | PROXIMAGEN LIMITED (GB) | 2011-05-17 | — | — | US | claimed |