Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.66 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | HTR1B | P28222 | 2/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1775352 | 0.99 | HTR6 (0.65) | HTR6HTR2CEPHX2HTR1AHTR1D | |
| SCHEMBL1778835 | 0.96 | HTR6 (0.62) | HTR6HTR2CEPHX2HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL1780272 | 0.95 | HTR6 (0.61) | HTR6HTR2CEPHX2HTR1AHTR1D | |
| SCHEMBL1774802 | 0.84 | HTR6 (0.76) | HTR6HTR2CHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL1774991 | 0.83 | HTR6 (0.74) | HTR6HTR2CHTR1ADRD2 | |
| SCHEMBL1776222 | 0.81 | HTR6 (0.68) | HTR6HTR2CHTR1AHTR1DHTR1B | |
| SCHEMBL1775376 | 0.80 | HTR6 (0.74) | HTR6HTR2CHTR1ADRD2 | |
| SCHEMBL1777219 | 0.80 | HTR6 (0.74) | HTR6HTR2CHTR1ADRD2 | |
| SCHEMBL1775290 | 0.80 | HTR6 (0.70) | HTR6HTR2CHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL1780081 | 0.80 | HTR6 (0.67) | HTR6HTR2CHTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943639-B2 | Such as 6-benzenesulfonyl-4-piperazin-1-yl-quinoline hydrochloride; for treatment of central nervous system and/or 5- HT6 receptor related disorders; for weight gain/loss | PROXIMAGEN LIMITED (GB) | 2011-05-17 | — | — | US | claimed |