SMC4

Structural maintenance of chromosomes protein 4 · Q9NTJ3 · SMC4 on Sugi Atlas →

0 patent compounds predicted against SMC4, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to SMC4 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Cornelia De Lange Syndrome: Assessing Positive Effects of Lithium Treatment PHASE2/PHASE3RECRUITING
Compared the Efficacy and Safety of CDOP Combined With Chidamide and CDOP in de Novo Peripheral T Cell Lymphoma Patients PHASE3UNKNOWN
Trial of the Histone-Deacetylase Inhibitor ITF2357 Followed by Mechlorethamine in Relapsed/Refractory Hodgkin's Lymphoma PHASE1/PHASE2COMPLETED
Study of Cytolytic Viral Activation Therapy (CVAT) for Recurrent/Metastatic Nasopharyngeal Carcinoma PHASE1UNKNOWN
Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome PHASE1COMPLETED
Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With Undetectable Viral Load PHASE1COMPLETED
Imetelstat for Children With Refractory or Recurrent Solid Tumors and Lymphoma PHASE1WITHDRAWN
Talazoparib for Cohesin-Mutated AML and MDS With Excess Blasts PHASE1ACTIVE_NOT_RECRUITING
Study of Synapsis and Recombination in Male Meiosis and the Implications in Infertility nanCOMPLETED
Studying The Role of Key Epigenetic Mediators in Breast Cancer Patients nanRECRUITING
Immunophenotyping and Xist Gene in AML nanUNKNOWN
Mesenchymal Stem Cells in NPM1 Mutated Low Risk Acute Myeloid Leukemia: a Study of the Tumor Microenvironment and Its Contribution to the Outcome nanCOMPLETED
Genetic Investigation of Solid Tumors Cohort nanCOMPLETED
Proteomic-Based Profiling of Lymphomas: Chromatin Proteomics; Composition and Modification of Histone and Non-Histone Chromosomal Proteins nanCOMPLETED
Telomeres Length in Israeli Fibrotic ILD Patients nanENROLLING_BY_INVITATION
Chromosome 18 Clinical Research Center nanRECRUITING
DNA Methylation and Autoimmune Thyroid Diseases nanCOMPLETED
Multi-Dimensional Genomic Dissection of Ring Chromosome 14 Syndrome nanACTIVE_NOT_RECRUITING
The Contribution of Optical Mapping to the Characterization of Chromosomal Rearrangements in Patients With Neurodevelopmental Disorders nanRECRUITING
Impact of Weight Loss on the Human Sperm Epitranscriptome nanACTIVE_NOT_RECRUITING
Telomeric Abnormalities in Colorectal Diseases by Fluorescent in Situ Hybridization Technique nanUNKNOWN
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia nanUNKNOWN
Diagnosis of Colorectal Cancer and Advanced Adenoma Using Cancer-specific Methylation Signatures nanUNKNOWN
Impact of Ionizing Treatment on the Nuclear Structure of Human Spermatozoa. nanUNKNOWN
Prenatal Cell-free DNA Screening in Pregnancies With Diverse Genetic Risk Profiles Utilizing Targeted and Whole-exome Sequencing nanNOT_YET_RECRUITING
Biological Aging Hallmarks-Guided Integrative TCM and Conventional Medicine in Post-Treatment Unexplained Female Infertility nanRECRUITING
SMYD3-Driven Metabolic Rewiring in Colorectal Liver Metastases nanNOT_YET_RECRUITING
Genetic of SportS Induced Endofibrotic Remodeling nanCOMPLETED
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact nanUNKNOWN
Nasal Brushing for the Diagnosis and Understanding of Telomeropathies nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a SMC4 binder may also engage these)

ProteinNameSimilarity
Q8CG47 1.000 Q8CG47 →
P50532 1.000 P50532 →
Q9ERA5 0.998 Q9ERA5 →
O93308 0.986 O93308 →
Q9FJL0 0.983 Q9FJL0 →
Q9CU62 0.982 Q9CU62 →
O97593 0.981 O97593 →
Q8CG48 0.981 Q8CG48 →
Q9CW03 0.980 Q9CW03 →
SMC3 Structural maintenance of chromosomes protein 3 0.980 landscape →
Q56YN8 0.979 Q56YN8 →
Q9C5Y4 0.977 Q9C5Y4 →
O97594 0.977 O97594 →
P50533 0.977 P50533 →
Q805A1 0.977 Q805A1 →
Q9LFS8 0.977 Q9LFS8 →
SMC1A Structural maintenance of chromosomes protein 1A 0.977 landscape →
O93309 0.976 O93309 →
Q5R4K5 0.976 Q5R4K5 →
SMC2 Structural maintenance of chromosomes protein 2 0.976 landscape →
Q9Z1M9 0.976 Q9Z1M9 →
P97690 0.975 P97690 →
Q802R9 0.974 Q802R9 →
Q9SN90 0.973 Q9SN90 →
Q00737 0.972 Q00737 →
E7F0W1 0.972 E7F0W1 →
Q8NDV3 0.971 Q8NDV3 →
Q920F6 0.970 Q920F6 →
Q90988 0.968 Q90988 →
Q54PK4 0.966 Q54PK4 →