Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ACACB | O00763 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17754293 | 0.87 | MAPT (0.40) | NPC1RAB9ASMN1; SMN2MAPTESR1 | |
| SCHEMBL15582413 | 0.86 | NPC1 (0.40) | NPC1RAB9ASMN1; SMN2MAPTACACB | |
| SCHEMBL17754279 | 0.86 | MAPT (0.40) | NPC1RAB9ASMN1; SMN2MAPTESR1 | |
| SCHEMBL17754344 | 0.85 | MAPT (0.49) | NPC1RAB9ASMN1; SMN2MAPTESR1 | |
| SCHEMBL17754294 | 0.85 | MAPT (0.49) | NPC1RAB9ASMN1; SMN2MAPTESR1 | |
| SCHEMBL13310805 | 0.82 | ESR1 (0.40) | NPC1RAB9ASMN1; SMN2MAPTESR1 | |
| SCHEMBL17754347 | 0.82 | MAPT (0.50) | NPC1RAB9ASMN1; SMN2MAPTESR1 | |
| SCHEMBL15582426 | 0.81 | KMT2A (0.41) | NPC1RAB9ASMN1; SMN2MAPTESR1 | |
| SCHEMBL17754278 | 0.81 | MAPT (0.43) | NPC1RAB9ASMN1; SMN2MAPTESR1 | |
| SCHEMBL19342373 | 0.79 | SMN1; SMN2 (0.41) | NPC1RAB9ASMN1; SMN2MAPTACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160137921-A1 | POLYMERIZABLE COMPOUND, AND LIQUID CRYSTAL COMPOSITION PRODUCED USING SAME | DIC CORPORATION (JP) | 2016-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137921-A1 | POLYMERIZABLE COMPOUND, AND LIQUID CRYSTAL COMPOSITION PRODUCED USING SAME | RCC1, LPXN, SMC4 | NPC1 2708/4885RAB9A 3948/4885SMN1; SMN2 3198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.